ArticleHypertension (Dallas, Tex. : 1979)2022
Prognostic Implications of Exercise-Induced Hypertension in Adults With Repaired Coarctation of Aorta.
Article in Hypertension (Dallas, Tex. : 1979), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Reverse Diagnostic Thinking for Aortic Coarctation Using the Renal Artery Bilateral Parvus et Tardus as a Clue: A Case Report.Clinical case reports · 2026Article
- Associations Between Exercise Blood Pressure Responses and Oxygen Pulse During Cardiopulmonary Exercise Testing: A Cross-Sectional Study.International journal of general medicine · 2026Article
- Hemodynamics of Exercise-Induced Hypertension and Relationship to Outcomes in Adults With Coarctation of the Aorta.Circulation. Heart failure · 2025Article
- Hypertension in aortic coarctation.Frontiers in cardiovascular medicine · 2025Review
- Prognostic implications of residual mild coarctation gradient after interventional repair.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Influence of Aortic Arch Morphology on Renal Perfusion in Patients with Coarctation of the Aorta: An Exploratory Study.Medicina (Kaunas, Lithuania) · 2024Article
- Article
- From Crafoord's End-to-End Anastomosis Approach to Percutaneous Interventions: Coarctation of the Aorta Management Strategies and Reinterventions.Journal of clinical medicine · 2023Review
- Coarctation of the Aorta: Modern Paradigms Across the Lifespan.Hypertension (Dallas, Tex. : 1979) · 2023Review
- Coarctation of the Aorta: Diagnosis and Management.Diagnostics (Basel, Switzerland) · 2023Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe purpose of this study was to assess the relationship between exercise-induced hypertension (EIH) and cardiovascular events, and to determine whether exercise blood pressure (BP) improved risk stratification in adults with repaired coarctation of aorta.
methodsRetrospective study of patients with repaired coarctation of aorta on antihypertensive therapy that underwent exercise testing and exercise test (2003-2019). BP was measured at rest in 3 different clinical settings and averaged to determine the resting BP. Indices of left ventricular function and afterload were obtained from the echocardiogram. EIH was defined as systolic BP >210 (males) or >190 (females) at peak exercise. Cardiovascular event was defined as atrial fibrillation, ventricular tachycardia, heart failure hospitalization, heart transplant, and cardiovascular death.
resultsOf 327 patients (age 35±13 years), 116 (35%) had EIH. Although the resting BP was similar between patients with versus without EIH, the EIH group had higher pulsatile arterial load, more advanced left ventricular remodeling, and were less likely to be on angiotensin converting enzyme inhibitor/angiotensin receptor blocker. EIH was associated with cardiovascular events (hazard ratio, 1.06 [95% CI, 1.02-1.08]) independent of resting systolic BP, and improved prognostic accuracy above resting systolic BP (
conclusionsEIH was associated with cardiovascular events independent of resting BP, and patients receiving angiotensin-converting enzyme inhibitor/angiotensin receptor blocker had lower risk of cardiovascular events. These data suggest that exercise BP could be used to assess adequacy of antihypertensive therapy, and to guide titration of antihypertensive therapy.
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