Evidence map›Paper›PMID 36252052›Full record

ArticleCirculation research2022

MonOrail to Cure? Targeting Orai1 to Reverse Pulmonary Arterial Hypertension.

Tatiana V Kudryashova, Elena A Goncharova

Open access · greenAbstract readEditorialComment
In one paragraph

Article in Circulation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tatiana V KudryashovaLung Center, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, Davis School of Medicine.ORCID 0000-0002-2843-5554
Elena A GoncharovaLung Center, Division of Pulmonary, Critical Care and Sleep Medicine, University of California, Davis School of Medicine.ORCID 0000-0001-7118-6752
University of California System · US

Funding

HIPPO Signaling in Pulmonary Arterial HypertensionR01HL130261 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GONCHAROVA, ELENA · 2016 to 2023
$3.5M
TSC2 Signaling in Pulmonary Arterial HypertensionR01HL113178 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GONCHAROVA, ELENA · 2012 to 2021
$3.1M
GATA-6 in pulmonary arterial hypertensionR01HL150638 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GONCHAROVA, ELENA, TROJANOWSKA, MARIA · 2020 to 2023
$2.6M
NHLBI NIH HHS R01 HL113178NHLBI NIH HHS R01 HL130261NHLBI NIH HHS R01 HL150638
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pulmonary Arterial HypertensionCell ProliferationCells, CulturedHumansMuscle, Smooth, VascularMyocytes, Smooth MuscleORAI1 ProteinPulmonary ArteryVascular RemodelingORAI1 ProteinORAI1 protein, humanEditorialshypertension, pulmonarymuscle, smooth, vascularORAI1 Proteinpulmonary arterytranslational science, biomedicalvascular remodeling

Identifiers

PMID36252052
PMCPMC9586488
OpenAlexW4305071813

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.