Evidence map›Paper›PMID 36252037›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Socioeconomic inequalities in molecular risk for chronic diseases observed in young adulthood.

Michael J Shanahan, Steven W Cole, Sudharshan Ravi, Justin Chumbley, Wenjia Xu, Cecilia Potente, Brandt Levitt, Julien Bodelet, Allison Aiello, Lauren Gaydosh and 1 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Socioeconomic inequalities in molecular risk for chronic diseases observed in young adulthood.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Michael J ShanahanJacobs Center for Productive Youth Development, University of Zürich, Zürich, CH 8050.ORCID 0000-0003-2139-3459
Steven W ColeSchool of Medicine, University of California, Los Angeles, Los Angeles, CA 90095.ORCID 0000-0002-7168-8039
Sudharshan RaviJacobs Center for Productive Youth Development, University of Zürich, Zürich, CH 8050.ORCID 0000-0001-6059-5403
Justin ChumbleyJacobs Center for Productive Youth Development, University of Zürich, Zürich, CH 8050.
Wenjia XuJacobs Center for Productive Youth Development, University of Zürich, Zürich, CH 8050.
Cecilia PotenteJacobs Center for Productive Youth Development, University of Zürich, Zürich, CH 8050.
Brandt LevittCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516.
Julien BodeletJacobs Center for Productive Youth Development, University of Zürich, Zürich, CH 8050.
Allison AielloCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516.ORCID 0000-0001-7029-2537
Lauren GaydoshDepartment of Sociology, University of Texas at Austin, Austin, TX 78712.ORCID 0000-0002-0036-626X
Kathleen Mullan HarrisCarolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516.ORCID 0000-0001-9757-1026

Funding

Wave IV Data CollectionP01HD031921 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 1994 to 2020
$86.1M
USC/UCLA Center on Biodemography &Population HealthP30AG017265 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE, HIRAM BELTRAN-SANCHEZ · 1999 to 2026
$17.9M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Social Context, the Life Course, and Genetic Transcription in Add HealthR01HD087061 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HARRIS, KATHLEEN MULLAN · 2016 to 2020
$3.0M
Social regulation of pro-inflammatory monocytesR01AG043404 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COLE, STEVE W · 2014 to 2018
$1.6M
Social Regulation of Gene ExpressionR01AG033590 · NIA · UNIVERSITY OF CHICAGO · PI CACIOPPO, STEPHANIE · 2018 to 2019
$720k
NIA NIH HHS P30 AG017265NIA NIH HHS R01 AG033590NIA NIH HHS R01 AG043404NICHD NIH HHS P01 HD031921NICHD NIH HHS P2C HD050924NICHD NIH HHS R01 HD087061
6 · The paper itself

Abstract

Many common chronic diseases of aging are negatively associated with socioeconomic status (SES). This study examines whether inequalities can already be observed in the molecular underpinnings of such diseases in the 30s, before many of them become prevalent. Data come from the National Longitudinal Study of Adolescent to Adult Health (Add Health), a large, nationally representative sample of US subjects who were followed for over two decades beginning in adolescence. We now have transcriptomic data (mRNA-seq) from a random subset of 4,543 of these young adults. SES in the household-of-origin and in young adulthood were examined as covariates of

Indexed as

Social ClassAdolescentAdultBody Mass IndexChronic DiseaseHumansLongitudinal StudiesRNA, MessengerSocioeconomic FactorsYoung AdultRNA, Messengerbiodemographylife-span developmentsocial epidemiologysocial genomicssocial inequality

Identifiers

PMID36252037
PMCPMC9621370

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.