ArticleProceedings of the National Academy of Sciences of the United States of America2022
Calibration-free, high-precision, and robust terahertz ultrafast metasurfaces for monitoring gastric cancers.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- Loss-Engineered Terahertz Pixelated Metasensors for Enhanced Molecular Vibrational Fingerprint Sensing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Quasi-Bound State in the Continuum-Driven Co-Frequency Polarization-Multiplexed Tunable Terahertz All Dielectric Metasurface.Nanomaterials (Basel, Switzerland) · 2026Article
- On-chip terahertz metasensor for quantitative multi-component biomolecular identification.Light, science & applications · 2026Article
- A Dual-Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- All-LCP Terahertz Metasensor with Dual Quasi-BIC Resonances for Dual-Range Refractive Index Sensing.Biosensors · 2026Article
- Highly Sensitive Detection and Discrimination of Cell Suspension Based on a Metamaterials-Based Biosensor Chip.Biosensors · 2026Article
- Eye-Tracking-Driven Programming Metasurface System for Adaptive Beam Focusing and Polarization-Agile Communication.Research (Washington, D.C.) · 2026Article
- Terahertz asynchronous twin-comb for prefiguring hypersensitivity beyond spectrum domain.Nature communications · 2025Article
- Terahertz's silent revolution in physics, engineering, and life science: Beyond the spectrum.Fundamental research · 2025Review
- Computational study of terahertz-driven controllable molecular isomerization.Nature communications · 2025Article
- Deep learning-assisted terahertz intelligent detection and identification of cancer tissue.Fundamental research · 2025Article
- Terahertz channels in atmospheric conditions: Propagation characteristics and security performance.Fundamental research · 2025Review
- The theory, technology, and application of terahertz metamaterial biosensors: A review.Fundamental research · 2025Review
- Enabling beam-scanning antenna technologies for terahertz wireless systems: A review.Fundamental research · 2025Review
- Terahertz Metamaterials Inspired by Quantum Phenomena.Research (Washington, D.C.) · 2025Review
- Terahertz Science and Technology in Astronomy, Telecommunications, and Biophysics.Research (Washington, D.C.) · 2025Review
- Integrated Single-Step Terahertz Metasensing for Simultaneous Detection Based on Exosomal Membrane Proteins Enables Pathological Typing of Gastric Cancer.Research (Washington, D.C.) · 2025Article
- Dynamic Polarization Control of Nonlinear Terahertz Photoresponse via Topological Phase Transitions.Research (Washington, D.C.) · 2025Article
- Advances in Terahertz Biophysics and Chemistry.Research (Washington, D.C.) · 2025Review
- Recent Advances in Metasurfaces: From THz Biosensing to Microwave Wireless Communications.Research (Washington, D.C.) · 2025Review
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18 authors.
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Abstract
Optical sensors, with great potential to convert invisible bioanalytical response into readable information, have been envisioned as a powerful platform for biological analysis and early diagnosis of diseases. However, the current extraction of sensing data is basically processed via a series of complicated and time-consuming calibrations between samples and reference, which inevitably introduce extra measurement errors and potentially annihilate small intrinsic responses. Here, we have proposed and experimentally demonstrated a calibration-free sensor for achieving high-precision biosensing detection, based on an optically controlled terahertz (THz) ultrafast metasurface. Photoexcitation of the silicon bridge enables the resonant frequency shifting from 1.385 to 0.825 THz and reaches the maximal phase variation up to 50° at 1.11 THz. The typical environmental measurement errors are completely eliminated in theory by normalizing the Fourier-transformed transmission spectra between ultrashort time delays of 37 ps, resulting in an extremely robust sensing device for monitoring the cancerous process of gastric cells. We believe that our calibration-free sensors with high precision and robust advantages can extend their implementation to study ultrafast biological dynamics and may inspire considerable innovations in the field of medical devices with nondestructive detection.
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