Evidence map›Paper›PMID 36251988›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Paradoxical self-sustained dynamics emerge from orchestrated excitatory and inhibitory homeostatic plasticity rules.

Saray Soldado-Magraner, Michael J Seay, Rodrigo Laje, Dean V Buonomano

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Homeostatic Plasticity Enables Stable yet Tunable Neuronal Assemblies.bioRxiv : the preprint server for biology · 2026
    Article
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  6. Review
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  12. Network state transitions during cortical development.Nature reviews. Neuroscience · 2024
    Review
  13. Synapse-type-specific competitive Hebbian learning forms functional recurrent networks.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Creation of Neuronal Ensembles and Cell-Specific Homeostatic Plasticity through Chronic Sparse Optogenetic Stimulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Saray Soldado-MagranerDepartment of Neurobiology, University of California, Los Angeles, CA 90095.ORCID 0000-0003-4890-2671
Michael J SeayDepartment of Neurobiology, University of California, Los Angeles, CA 90095.
Rodrigo LajeDepartamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Bernal, B1876BXD Argentina.ORCID 0000-0003-1481-303X
Dean V BuonomanoDepartment of Neurobiology, University of California, Los Angeles, CA 90095.

Funding

Multiplexing working memory and timing: Encoding retrospective and prospective information in transient neural trajectories.R01NS116589 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BUONOMANO, DEAN V, GOLSHANI, PEYMAN · 2023 to 2024
$1.2M
HHS | National Institutes of Health (NIH) NS116589NINDS NIH HHS R01 NS116589
6 · The paper itself

Abstract

Self-sustained neural activity maintained through local recurrent connections is of fundamental importance to cortical function. Converging theoretical and experimental evidence indicates that cortical circuits generating self-sustained dynamics operate in an inhibition-stabilized regime. Theoretical work has established that four sets of weights (

Indexed as

Nerve NetNeuronal PlasticityBrainHomeostasisLearningModels, Neurologicalhomeostatic plasticityinhibition-stabilized networksparadoxical effect

Identifiers

PMID36251988
PMCPMC9618084

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.