Evidence map›Paper›PMID 36251744›Full record

ArticleBlood advances2022

Clofarabine treatment of KMT2Ar infantile patients with acute lymphoblastic leukemia in St. Jude Total Therapy Study 16.

Tanja A Gruber, Deqing Pei, John Choi, Cheng Cheng, Elaine Coustan-Smith, Dario Campana, Hope D Swanson, Jennifer L Pauley, Hiroto Inaba, Monika L Metzger and 5 more

Abstract read
In one paragraph

Article in Blood advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Infant Acute Lymphoblastic Leukemia-New Therapeutic Opportunities.International journal of molecular sciences · 2024
    Review
  3. Updates inBiomedicines · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tanja A GruberDepartment of Pediatrics, Stanford University School of Medicine, Stanford, CA.ORCID 0000-0003-1072-7257
Deqing PeiDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN.
John ChoiDepartment of Pathology, University of Alabama at Birmingham, Birmingham, AL.ORCID 0000-0002-2861-0180
Cheng ChengDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN.
Elaine Coustan-SmithDepartment of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Dario CampanaDepartment of Pediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Hope D SwansonDepartment of Pharmacy and Pharmaceutical Sciences.
Jennifer L PauleyDepartment of Global Pediatric Medicine.
Hiroto InabaDepartment of Oncology.
Monika L MetzgerDepartment of Global Pediatric Medicine.
Jeffrey E RubnitzDepartment of Oncology.ORCID 0000-0001-9885-3527
Raul C RibeiroDepartment of Oncology.ORCID 0000-0002-9956-5647
Susana C RaimondiDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN.
Ching-Hon PuiDepartment of Global Pediatric Medicine.ORCID 0000-0003-0303-5658
Sima JehaDepartment of Global Pediatric Medicine.

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI CHARLES ROBERTS · 1985 to 2026
$166.9M
CPML - Project 3: Genome-wide Studies of Adverse EffectsP50GM115279 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI LOH, MIGNON LEE-CHEUN, RELLING, MARY V · 2015 to 2019
$15.1M
PHARMACOGENOMICS OF CHILDHOOD LEUKEMIA (ALL)R37CA036401 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI EVANS, WILLIAM E · 1987 to 2014
$9.7M
Pharmacogenomics of Childhood Leukemia ALLR01CA036401 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI EVANS, WILLIAM E · 1985 to 2019
$3.6M
NCI NIH HHS P30 CA021765NCI NIH HHS R01 CA036401NCI NIH HHS R37 CA036401NIGMS NIH HHS P50 GM115279
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Precursor Cell Lymphoblastic Leukemia-LymphomaAntineoplastic Combined Chemotherapy ProtocolsClofarabineHumansClofarabine

Identifiers

PMID36251744
PMCPMC9768237

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.