Observational studyInternational wound journal2023
The effect of inflammation management on pH, temperature, and bacterial burden.
Observational study in International wound journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Clinical Utility of Autofluorescence Imaging for Bacterial Detection in Wounds: A Systematic Review.International wound journal · 2025Pooled it
- Optimal Wound pH and Related Factors in the Healing Process of Diabetes-Related Foot Ulcer: A Prospective Observational Study.Health science reports · 2026Article
- The Role of Thermal Immunomodulation in Postoperative Wound Repair with a Focus on Hepatic Surgery.International journal of molecular sciences · 2026Review
- Autofluorescence properties of wound-associated bacteria cultured under various temperature, salinity, and pH conditions.BMC microbiology · 2025Article
- Measurement and Sequelae of Neonatal Skin Injuries: A Prospective Diagnostic/Feasibility Study.International wound journal · 2025Article
- Towards Intelligent Wound Care: Hydrogel-Based Wearable Monitoring and Therapeutic Platforms.Polymers · 2025Review
- Glucose oxidase: An emerging multidimensional treatment option for diabetic wound healing.Bioactive materials · 2025Review
- [Application of delayed replantation of degloving skin preserved at 4Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025Article
- Diabetic foot ulcer healing with polylactic acid membrane assessed by thermographic imaging: a case report.Frontiers in medicine · 2025Article
- Flexible bioelectronic systems with large-scale temperature sensor arrays for monitoring and treatments of localized wound inflammation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Smart photonic crystal hydrogels for visual glucose monitoring in diabetic wound healing.Journal of nanobiotechnology · 2024Article
- Cooling wound dressings: Prospects for clinical practice.Clinical and translational medicine · 2024Article
- Can pin-site inflammation be detected with thermographic imaging? A cross-sectional study from the USA and Denmark of patients treated with external fixators.Acta orthopaedica · 2024Article
- Intelligent electrospinning nanofibrous membranes for monitoring and promotion of the wound healing.Materials today. Bio · 2024Review
- Integrating Point-of-Care Bacterial Fluorescence Imaging-Guided Care with Continued Wound Measurement for Enhanced Wound Area Reduction Monitoring.Diagnostics (Basel, Switzerland) · 2023Article
- The effect of inflammation management on pH, temperature, and bacterial burden.International wound journal · 2023Observational
- Is my wound infected? A study on the use of hyperspectral imaging to assess wound infection.Frontiers in medicine · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The aim of this feasibility study was to investigate the impact of inflammation management on wound pH, temperature, and bacterial burden, using the principles of TIME and Wound Bed Preparation. A quantitative non-comparative, prospective, descriptive observational design. Following ethical approval, 26 participants with 27 wounds of varying aetiologies were observed twice weekly for 2 weeks. Wounds were treated with cleansing, repeated sharp debridement, and topical cadexomer iodine. Wound pH (pH indicator strips), temperature (infrared camera), bacterial burden (fluorescence imaging) and size (ruler method) was monitored at each visit. The mean age of all participants was 47 years (SD: 20.3 years), and 79% (n = 19) were male, and most wounds were acute (70%; n = 19) and included surgical and trauma wounds, the remaining (30%; n = 8) were chronic and included vascular ulcers and non-healing surgical wounds. Mean wound duration was 53.88 days (SD: 64.49 days). Over the follow up period, pH values ranged from 6 to 8.7, temperature (centre spot) ranged from 28.4°C to 36.4°C and there was an average 39% reduction in wound size. Inflammation management had a positive effect on pH, temperature, bacterial burden, and wound size. This study demonstrated that it was feasible to practice inflammation management using a structured approach to enhance wound outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.