Evidence map›Paper›PMID 36251145›Full record

ArticleClinical and experimental medicine2023

NCX1 disturbs calcium homeostasis and promotes RANKL-induced osteoclast differentiation by regulating JNK/c-Fos/NFATc1 signaling pathway in multiple myeloma.

Tingting Li, Dongbiao Qiu, Qingjiao Chen, Apeng Yang, Junmin Chen, Zhiyong Zeng

Open access · hybridAbstract read
In one paragraph

Article in Clinical and experimental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. NCX1/CaCell communication and signaling : CCS · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tingting LiDepartment of Hematology, The First Affiliated Hospital of Fujian Medical University, 20 Chazhong Road, Fuzhou, 350005, Fujian, People's Republic of China.
Dongbiao QiuDepartment of Blood Transfusion, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People's Republic of China.
Qingjiao ChenDepartment of Hematology, The First Affiliated Hospital of Fujian Medical University, 20 Chazhong Road, Fuzhou, 350005, Fujian, People's Republic of China.
Apeng YangDepartment of Hematology, The First Affiliated Hospital of Fujian Medical University, 20 Chazhong Road, Fuzhou, 350005, Fujian, People's Republic of China.
Junmin ChenDepartment of Hematology, The First Affiliated Hospital of Fujian Medical University, 20 Chazhong Road, Fuzhou, 350005, Fujian, People's Republic of China. drjunminchen@hotmail.com.
Zhiyong ZengDepartment of Hematology, The First Affiliated Hospital of Fujian Medical University, 20 Chazhong Road, Fuzhou, 350005, Fujian, People's Republic of China. zengzhiyong049@163.com.
Fujian Medical University · CNFirst Affiliated Hospital of Fujian Medical University · CN

Funding

Sailing Fund of Fujian Medical University 2021QH2041the National Natural Science Foundation of China No. 81400160the National Natural Science Foundation of China No. 82070218the Natural Science Foundation of Fujian Province 2022J02036
6 · The paper itself

Abstract

Although several types of calcium channels abnormalities have been shown to promote myeloma bone disease (MBD), the relationship between Na

Indexed as

Multiple MyelomaOsteoclastsCalciumCell DifferentiationHomeostasisHumansNFI Transcription FactorsRANK LigandSignal TransductionSodium-Calcium ExchangerThioureaT-Lymphocytes2-(2-(4-(4-nitrobenzyloxy)phenyl)ethyl)isothiourea methanesulfonateCalciumNFI Transcription FactorsRANK LigandSodium-Calcium Exchangersodium-calcium exchanger 1ThioureaTNFSF11 protein, humanCalciumMultiple myelomaNCX1 channelOsteoclast differentiation

Identifiers

PMID36251145
PMCPMC10460717
OpenAlexW4306403590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.