Evidence map›Paper›PMID 36251126›Full record

Observational studyArchives of osteoporosis2022

The interdisciplinary fracture liaison service improves health-related outcomes and survival of older adults after hip fracture surgical repair.

Carmelinda Ruggiero, Marta Baroni, Giuseppe Rocco Talesa, Alessandro Cirimbilli, Valentina Prenni, Valentina Bubba, Luca Parretti, Riccardo Bogini, Giuliana Duranti, Auro Caraffa and 3 more

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Archives of osteoporosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  14. Fracture liaison service evaluation during admission for fragility femur fracture increases rates of bone health intervention and outpatient follow-up.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  15. Observational
  16. Pre-fracture functional status and 30-day recovery predict 5-year survival in patients with hip fracture: findings from a prospective real-world study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Observational
  17. Sentinel fracture: the necessity of improved post-fracture care.Wiener medizinische Wochenschrift (1946) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Carmelinda RuggieroSection of Gerontology and Geriatric, Department of Medicine and Surgery, S.M. Misericordia Hospital of Perugia, University of Perugia, S. Andrea Delle Fratte, Perugia, Italy. carmelinda.ruggiero@unipg.it.ORCID http://orcid.org/0000-0002-1245-1963
Marta BaroniSection of Gerontology and Geriatric, Department of Medicine and Surgery, S.M. Misericordia Hospital of Perugia, University of Perugia, S. Andrea Delle Fratte, Perugia, Italy.
Giuseppe Rocco TalesaSection of Orthopedics and Traumatology, Department of Medicine and Surgery, S.M. Misericordia Hospital, University of Perugia, Sant'Andrea Delle Fratte, Perugia, Italy.
Alessandro CirimbilliSection of Orthopedics and Traumatology, Department of Medicine and Surgery, S.M. Misericordia Hospital, University of Perugia, Sant'Andrea Delle Fratte, Perugia, Italy.
Valentina PrenniSection of Gerontology and Geriatric, Department of Medicine and Surgery, S.M. Misericordia Hospital of Perugia, University of Perugia, S. Andrea Delle Fratte, Perugia, Italy.
Valentina BubbaSection of Gerontology and Geriatric, Department of Medicine and Surgery, S.M. Misericordia Hospital of Perugia, University of Perugia, S. Andrea Delle Fratte, Perugia, Italy.
Luca ParrettiSection of Gerontology and Geriatric, Department of Medicine and Surgery, S.M. Misericordia Hospital of Perugia, University of Perugia, S. Andrea Delle Fratte, Perugia, Italy.
Riccardo BoginiPrimary Care Physicians - SIMG, ASL 201, Perugia, Italy.
Giuliana DurantiPrimary Care Physicians - SIMG, ASL 201, Perugia, Italy.
Auro CaraffaSection of Orthopedics and Traumatology, Department of Medicine and Surgery, S.M. Misericordia Hospital, University of Perugia, Sant'Andrea Delle Fratte, Perugia, Italy.
Virginia BoccardiSection of Gerontology and Geriatric, Department of Medicine and Surgery, S.M. Misericordia Hospital of Perugia, University of Perugia, S. Andrea Delle Fratte, Perugia, Italy.
Patrizia MecocciSection of Gerontology and Geriatric, Department of Medicine and Surgery, S.M. Misericordia Hospital of Perugia, University of Perugia, S. Andrea Delle Fratte, Perugia, Italy.
Giuseppe RinonapoliSection of Orthopedics and Traumatology, Department of Medicine and Surgery, S.M. Misericordia Hospital, University of Perugia, Sant'Andrea Delle Fratte, Perugia, Italy.
University of Perugia · ITSocietà Italiana di Medicina Generale · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the high burden of fragility fractures, we developed an interdisciplinary FLS care pathway for early management and monitoring of older adults discharged from a high-volume trauma center after hip fracture repair. Interdisciplinary FLS effectively improves up to 1-year adherence to treatments for secondary prevention of fragility fractures, reduces health facility admission, and improves long-term survival. PURPOSE: To compare adherence to secondary fragility fracture prevention, falls, healthcare facility admissions, and mortality between hip fracture older adults who entered the fracture liaison services pathway of care (FLS-CP) and those managed according to the usual traumatologist model of care (U-CP).

methodsProspective observational study enrolling subjects aged ≥ 65 years discharged by high-volume trauma center after hip fracture repair from February 2016 to February 2017, who consecutively entered FLS-CP or U-CP according to their preference and goals.

resultsCompared to U-CP, those in FLS-CP had higher initiation rate and up to 1-year adherence to secondary prevention of fragility fracture, including vitamin D and calcium (87.7% vs 36.9%; p < 0.0001), specific anti-osteoporosis drugs (75.1% vs 8.0%; p < 0.0001), and complete anti-fracture therapy (72.3% vs 5.7%; p < 0.0001). Older adults belonging to FLS-CP showed a lower likelihood of healthcare facility admission (RR 0.597; 95% CI 0.398-0.895; p = 0.0125), with a longer re-hospitalization-free survival (176.4 vs 88.7 days; p = 0.0152) than those in U-CP. One-year incidence of falls and fractures was similar between groups, with a lower tendency of the subjects in the FLS-CP to be multiple fallers (19% vs 34.8%; OR 0.057; 95% CI 0.004-0.876; p = 0.0690). The FLS-CP group experienced a lower 1-year (87.2% vs 74.3%; p = 0.001) and 3-year mortality (67.9% vs 55.6%; p = 0.0245) and a lower adjusted 5-year mortality hazard ratio (50.2% vs 58%; HR = 0.76; 95% CI 0.60; 0.96).

conclusionThe FLS-CP may improve initiation and adherence to secondary prevention of fragility fractures, reduces healthcare facility admission, and improves long-term survival.

Indexed as

Bone Density Conservation AgentsHip FracturesOsteoporosisOsteoporotic FracturesAgedCalciumHumansSecondary PreventionVitamin DBone Density Conservation AgentsCalciumVitamin DAnti-osteoporosis treatmentsFracture liaison serviceFragility fracturesHip fractureOsteoporosis

Identifiers

PMID36251126
PMCPMC9576663
OpenAlexW4306404257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.