SynthesisArchives of gynecology and obstetrics2023
Effect of bacterial vaginosis on preterm birth: a meta-analysis.
Synthesis in Archives of gynecology and obstetrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Risk of HSV-2 Acquisition Among Women with Bacterial Vaginosis: Systematic Review and Meta-Analysis.Viruses · 2026Pooled it
- Randomized Study of Usual Care Versus Xpert ® Xpress Multiplex Vaginal Panel at the Point-of-Care for Accurate Diagnosis and Appropriate Treatment of Vaginal Infections.Sexually transmitted diseases · 2026Trial
- Sertaconazole 300 mg versus clotrimazole 500 mg vaginal suppository for treating pregnant women with acute vaginal candidiasis: a double-blinded, randomized trial.BMC pregnancy and childbirth · 2024Trial
- Comparing BD Affirm VPIII to Xpert Xpress MVP and BD MAX Vaginal Panel for the diagnosis of vaginal infections.Microbiology spectrum · 2026Article
- Fetal Heart Rate at 12 Weeks' Gestation and the Risk of Preterm Birth: A Prospective Validation Study.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026Article
- Study of microbe-microbe interactions between the sexually transmitted parasitebioRxiv : the preprint server for biology · 2026Article
- Role of vulvovaginal infection in women with short cervix: An observational clinical trial.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Observational
- LPS-induced endometrial cell-derived exosomes suppress probiotic Lactobacillus growth.Scientific reports · 2026Article
- Underexplored maternal microbiomes: immune, metabolic, and microbial pathways shaping pregnancy outcomes.Infection and immunity · 2026Review
- Bacterial vaginosis: a narrative review of concepts and best practices.Gynecology and pelvic medicine · 2026Review
- Bacterial vaginosis in early pregnancy and birth outcomes: Evidence from a prospective cohort in the middle belt of Ghana.PloS one · 2026Article
- Old but gold: an historical perspective of wet mount microscopy and its current role for the diagnosis of vaginitis.Frontiers in reproductive health · 2026Review
- Prevalence ofInternational journal of women's health · 2026Article
- Oral, Vaginal, and Placental Microbiota Profiles in Japanese Pregnancies with Preterm Birth and Chronic Abruption-Oligohydramnios Sequence (CAOS): A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2025Article
- Profiling of vaginal microbial communities in Chilean women via self-sampling and nanopore sequencing.Scientific reports · 2025Article
- Vaginal microbiome and its implications in preterm birth.Obstetrics & gynecology science · 2025Review
- Sialidases derived frombioRxiv : the preprint server for biology · 2025Article
- Association between body mass index and the risk of bacterial vaginosis: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2025Article
- Sexually transmitted infections and bacterial vaginosis and preterm birth in pregnant people living with HIV: A population-based cohort study.International journal of STD & AIDS · 2025Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
purposeBacterial vaginosis is a common genital tract disorder. It can lead to preterm birth, but its contribution is equivocal. Bacterial vaginosis is curable and, if diagnosed and appropriately treated, may reduce preterm births. The study desired to confirm the association between bacterial vaginosis and preterm birth.
methodsIt was a meta-analysis. We included articles published from 2008 to 2022. The authors included studies that measured the association between bacterial vaginosis and preterm birth by relative risk/risk ratio (RR) or odds ratio (OR). We excluded studies with qualitative data. The study utilized five search engines, PubMed, Scopus, Google Scholar, Cochrane, and LILAC. We used the statistical package for social sciences (SPSS) to draw forest and funnel plots separately for RR and OR.
resultsAfter an extensive search, the study included 20 articles yielding 26 relevant results with a total of 290,397 observations. This meta-analysis proves that bacterial vaginosis is undoubtedly associated with preterm birth. The overall relative risk of preterm delivery is about two-fold as overall OR1.79 (95% Confidence Interval 1.32-2.43). The overall RR of preterm birth is 1.44 (95% Confidence Interval 1.19-1.73).
conclusionOur study shows a significant association between bacterial vaginosis and preterm birth. The study concludes that investigation for bacterial vaginosis and management should be a part of the routine examination of a pregnant woman. The health system must initiate this strategy soon to reduce the prevalence of preterm births and consequent neonatal mortality.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.