Evidence map›Paper›PMID 36251028›Full record

ArticleCancer immunology, immunotherapy : CII2023

Peptide vaccine from cancer-testis antigen ODF2 can potentiate the cytotoxic T lymphocyte infiltration through IL-15 in non-MSI-H colorectal cancer.

Ranran Shi, Xiuman Zhou, Liwei Pang, Mingshuang Wang, Yubing Li, Chunxia Chen, Haoming Ning, Lihan Zhang, Guangxing Yue, Lu Qiu and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer immunology, immunotherapy : CII, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. The role of CD8Heliyon · 2024
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Ranran ShiSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Xiuman ZhouSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, China.
Liwei PangSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Mingshuang WangSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Yubing LiSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Chunxia ChenSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Haoming NingSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Lihan ZhangDepartment of Integrated Chinse and Western Medicine, Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, 450008, China.
Guangxing YueDepartment of Integrated Chinse and Western Medicine, Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou, 450008, China.
Lu QiuSchool of Pharmaceutical Sciences (Shenzhen), Sun Yat-sen University, Shenzhen, 518107, China.
Wenshan ZhaoSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Yuanming QiSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China.
Yahong WuSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China. yahongwu@zzu.edu.cn.
Yanfeng GaoSchool of Life Sciences, Zhengzhou University, Zhengzhou, 450001, China. gaoyf29@mail.sysu.edu.cn.
Zhengzhou University · CNSun Yat-sen University · CNHenan Cancer Hospital · CN

Funding

National Science Foundation of China 81822043National Science Foundation of China 82002575National Science Foundation of China U1904147Project of Henan Province No. 212102310338, LHGJ20190673, 202002077
6 · The paper itself

Abstract

About 85% of patients with colorectal cancer (CRC) have the non-microsatellite instability-high (non-MSI-H) subtype, and many cannot benefit from immune checkpoint blockade. A potential reason for this is that most non-MSI-H colorectal cancers are immunologically "cold" due to poor CD8

Indexed as

Colorectal NeoplasmsT-Lymphocytes, CytotoxicAnimalsCancer VaccinesEpitopesHeat-Shock ProteinsInterleukin-15MaleMiceMice, Inbred NODMice, SCIDPeptidesTestisVaccines, SubunitCancer VaccinesEpitopesHeat-Shock ProteinsInterleukin-15Odf2 protein, mousePeptidesVaccines, SubunitCancer immunotherapyCancer-testis antigenImmune infiltrationNon-MSI-H colorectal cancerPeptide vaccine

Identifiers

PMID36251028
PMCPMC10991242
OpenAlexW4306392387

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.