Evidence map›Paper›PMID 36250999›Full record

ArticleMolecular pharmaceutics2022

Caffeic Acid-Grafted PLGA as a Novel Material for the Design of Fluvastatin-Eluting Nanoparticles for the Prevention of Neointimal Hyperplasia.

Stefano Bellosta, Francesca Selmin, Giulia Magri, Silvia Castiglioni, Patrizia Procacci, Patrizia Sartori, Edoardo Scarpa, Valerio Tolva, Clara Rossi, Francesco Puoci and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Biopolymers of Polycaprolactone Loaded with Caffeic Acid andInternational journal of molecular sciences · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Stefano BellostaDept. Pharmacological and Biomolecular Sciences, Università Degli Studi di Milan, Via G. Balzaretti 9, Milan20133, Italy.ORCID 0000-0001-5344-7824
Francesca SelminDept of Pharmaceutical Sciences, Università Degli Studi di Milano, via G. Colombo, 71, Milan20133, Italy.ORCID 0000-0002-3680-6124
Giulia MagriDept of Pharmaceutical Sciences, Università Degli Studi di Milano, via G. Colombo, 71, Milan20133, Italy.
Silvia CastiglioniDept. Pharmacological and Biomolecular Sciences, Università Degli Studi di Milan, Via G. Balzaretti 9, Milan20133, Italy.
Patrizia ProcacciDept of Biomedical Sciences for Health, Università Degli Studi di Milano, via G. Colombo, 71, Milan20133, Italy.
Patrizia SartoriDept of Biomedical Sciences for Health, Università Degli Studi di Milano, via G. Colombo, 71, Milan20133, Italy.
Edoardo ScarpaDept of Pharmaceutical Sciences, Università Degli Studi di Milano, via G. Colombo, 71, Milan20133, Italy.
Valerio TolvaStruttura Complessa di Chirurgia Vascolare, Fondazione "A. De Gasperis", ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore 3, Milan20162, Italy.
Clara RossiDept. Pharmacological and Biomolecular Sciences, Università Degli Studi di Milan, Via G. Balzaretti 9, Milan20133, Italy.
Francesco PuociDept of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende87036, Cosenza, Italy.
Loris RizzelloDept of Pharmaceutical Sciences, Università Degli Studi di Milano, via G. Colombo, 71, Milan20133, Italy.ORCID 0000-0002-8230-853X
Francesco CilurzoDept of Pharmaceutical Sciences, Università Degli Studi di Milano, via G. Colombo, 71, Milan20133, Italy.ORCID 0000-0003-3560-291X
University of Milan · ITOspedale Maggiore · ITUniversity of Calabria · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug-eluting nanoparticles (NPs) administered by an eluting balloon represent a novel tool to prevent restenosis after angioplasty, even if the selection of the suitable drug and biodegradable material is still a matter of debate. Herein, we provide the proof of concept of the use of a novel material obtained by combining the grafting of caffeic acid or resveratrol on a poly(lactide-

Indexed as

NanoparticlesPolyglycolic AcidCaffeic AcidsDrug CarriersEndothelial CellsFluvastatinHumansHyperplasiaLactic AcidPolylactic Acid-Polyglycolic Acid Copolymercaffeic acidCaffeic AcidsDrug CarriersFluvastatinLactic AcidPolyglycolic AcidPolylactic Acid-Polyglycolic Acid Copolymerconfocal microscopyDILfluvastatinprolonged releaseresveratrolsilver nanoparticle

Identifiers

PMID36250999
PMCPMC9937560
OpenAlexW4306409547

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.