Evidence map›Paper›PMID 36250256›Full record

ArticleFEBS letters2023

Tryptophan-96 in cytochrome P450 BM3 plays a key role in enzyme survival.

Raheleh Ravanfar, Yuling Sheng, Harry B Gray, Jay R Winkler

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in FEBS letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. From single step hops to emergent biological phenomena.Journal of inorganic biochemistry · 2026
    Review
  2. Oxidizable amino acids around cytochrome P450 hemes.Journal of inorganic biochemistry · 2026
    Article
  3. Article
  4. Article
  5. Elucidating the Role of OACS environmental Au · 2024
    Article
  6. Article
  7. Tryptophan extends the life of cytochrome P450.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Raheleh RavanfarBeckman Institute, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0003-2992-0575
Yuling ShengBeckman Institute, California Institute of Technology, Pasadena, CA, USA.
Harry B GrayBeckman Institute, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-7937-7876
Jay R WinklerBeckman Institute, California Institute of Technology, Pasadena, CA, USA.
California Institute of Technology · US

Funding

ELECTRON-TRANSFER PROCESSES IN IRON AND COPPER PROTEINSR01DK019038 · NIDDK · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI GRAY, HARRY B, WINKLER, JAY R · 1986 to 2023
$7.0M
NIDDK NIH HHS R01 DK019038
6 · The paper itself

Abstract

Flavocytochrome P450 from Bacillus megaterium (P450

Indexed as

Bacillus megateriumTryptophanBacterial ProteinsCytochrome P-450 Enzyme SystemHemeNADPH-Ferrihemoprotein ReductaseOxidation-ReductionTyrosineBacterial ProteinsCytochrome P-450 Enzyme SystemHemeNADPH-Ferrihemoprotein ReductaseTryptophanTyrosinecytochrome P450electron transfertotal turnover numbertryptophantyrosine

Identifiers

PMID36250256
PMCPMC9839481
OpenAlexW4306399501

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.