Evidence map›Paper›PMID 36250093›Full record

ArticleFrontiers in medicine2022

A poor perspective of self weight significantly increases adverse outcomes in non-alcoholic fatty liver disease (NAFLD).

Clarissa Elysia Fu, Cheng Han Ng, Nicholas W S Chew, Zane En Qi Heng, Yip Han Chin, Jingxuan Quek, Wen Hui Lim, Jieling Xiao, Kai En Chan, Darren Jun Hao Tan and 10 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 2 countries.

Clarissa Elysia FuYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Cheng Han NgYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Nicholas W S ChewYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Zane En Qi HengDivision of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore.
Yip Han ChinYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Jingxuan QuekYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Wen Hui LimYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Jieling XiaoYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Kai En ChanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Darren Jun Hao TanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Caitlyn TanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Sitong ZhangYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Teng Kiat KohDivision of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore.
Benjamin NahDivision of Gastroenterology and Hepatology, Department of Medicine, National University Hospital, Singapore, Singapore.
Yock Young DanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Nicholas SynYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Mohammad Shadab SiddiquiDivision of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, United States.
Arun J SanyalDivision of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, United States.
Mazen NoureddinHouston Research Institute, Houston Liver Institute, Houston, TX, United States.
Mark MuthiahYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
National University of Singapore · SGNational University Hospital · SGVirginia Commonwealth University · USHouston Institute for Clinical Research · USNational University Health System · SGNational University Heart Centre Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Non-alcoholic fatty liver disease (NAFLD) is prevalent amongst overweight and obese individuals, and weight loss remains the main mode of treatment for NAFLD patients. Weight perception plays a key role in the efficacy of such treatment. The current study aims to investigate the prevalence, associating factors and implications of poor weight perception amongst such individuals. Methods: An analysis was done on data collected from NHANES between 1999 and 2018. Comparison was made between NAFLD individuals with and without poor weight perception in terms of prevalence, associated characteristics, and clinical outcomes. Multivariate analysis was used to compare effect size of adverse events associated with NAFLD individuals with poor weight perception. Results: Of the 12,170 NAFLD patients, 19.2% (CI: 18.5 to 19.9%) had poor weight perception. Poor weight perception was significantly associated with lower education levels, reduced levels of exercise and unhealthier lipid profiles. There was an increased risk in all-cause mortality (HR: 1.18, CI: 1.00 to 1.38, Conclusion: This study highlights the positive association between appropriate weight perception and better outcomes in individuals with NAFLD. Poor weight perception increased the risk of adverse events and decreased inclination toward seeking weight loss treatment. Greater emphasis should be placed on dealing with weight perception in individuals with NAFLD for better treatment outcomes.

Indexed as

mortalityNAFLDNAFLD outcomesnon-alcoholic fatty liver diseaseweight perception

Identifiers

PMID36250093
PMCPMC9554148
OpenAlexW4297540269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.