Evidence map›Paper›PMID 36249991›Full record

ArticleOne health (Amsterdam, Netherlands)2022

Strengthening laboratory biosafety in Liberia during the COVID-19 pandemic: Experience from the Global Laboratory Leadership Programme.

Shruti Malik, Fahn M Taweh, Maxwell Freeman, John B Dogba, Grace O Gwesa, Melvin Tokpah, Prince P Gbondin, T Henry Kohar, John Y Hena, Jane A MaCauley and 5 more

Abstract read
In one paragraph

Article in One health (Amsterdam, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Shruti MalikIntegrated Quality Laboratory Services, 207 Rue Francis de Pressense, 69100 Villeurbanne, France.
Fahn M TawehNational Public Health Institute of Liberia, Congo Town Back Road, Monrovia, Liberia.
Maxwell FreemanNational Public Health Institute of Liberia, Congo Town Back Road, Monrovia, Liberia.
John B DogbaNational Public Health Institute of Liberia, Congo Town Back Road, Monrovia, Liberia.
Grace O GwesaNational Public Health Institute of Liberia, Congo Town Back Road, Monrovia, Liberia.
Melvin TokpahNational Standards Laboratory of Liberia, Lynch Street, Monrovia, Liberia.
Prince P GbondinMinistry of Health, Congo Town, Tubman Blvd, Monrovia, Liberia.
T Henry KoharMinistry of Health, Congo Town, Tubman Blvd, Monrovia, Liberia.
John Y HenaLeon Quist Ledlum Central Veterinary Laboratory, Ministry of Agriculture, Gardnesville, Monrovia, Liberia.
Jane A MaCauleyNational Public Health Institute of Liberia, Congo Town Back Road, Monrovia, Liberia.
Antoine PiersonIntegrated Quality Laboratory Services, 207 Rue Francis de Pressense, 69100 Villeurbanne, France.
Mark A RayfieldU.S. Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, Atlanta, GA 30329, USA.
Leonard F PeruskiU.S. Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, Atlanta, GA 30329, USA.
Adilya AlbetkovaU.S. Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, Atlanta, GA 30329, USA.
Amanda BalishU.S. Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, Atlanta, GA 30329, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Global Laboratory Leadership Programme (GLLP) has biosafety and biosecurity as one of its core competencies and advocates for a One Health approach involving all relevant sectors across the human-animal-environment interface to empower national laboratory systems and strengthen health security. Decentralization of SARS-CoV-2 testing in Liberia coupled with an increase in the number of COVID-19 infections among laboratory professionals raised biosafety concerns. In response, a set of trainings on laboratory biosafety was launched for lab personnel across the country under the framework of the GLLP. The goal was to deliver a comprehensive package for laboratory biosafety in the context of SARS-CoV-2 through active learning. Methods: Three one-day workshops were conducted between September and October 2020, training personnel from human, animal and environmental laboratories through a One Health approach. Concepts critical to laboratory biosafety were delivered in an interactive engagement format to ensure effective learning and retention of concepts. Pre- and post-training assessments were performed, and a paired Results: Of the 67 participants, 64 were from the human health sector, one from veterinary sector and two from environmental health sector. The average pre-test score was 41%. The main gaps identified were failure to acknowledge surgical antisepsis as a form of hand hygiene and recognition of PPE as the best risk control measure. The average post-test score was 75.5%. The mean difference of pre-test and post-test scores was statistically significant ( Conclusions: The workshops were impactful as evidenced by significant improvement (34.5%) in the post-test scores and positive participant feedback. Repeated refresher trainings are vital to addressing the gaps, ensuring compliance, and promoting biosafety culture. GLLP's approach to cultivating multisectoral national laboratory leaders ready to take responsibility and ownership for capacity building provides a sustainable solution for attaining strong national laboratory systems better prepared for health emergencies and pandemics like COVID-19.

Indexed as

COVID-19Global laboratory leadership programmeLaboratory biosafetyOne healthSARS-CoV-2Workforce development

Identifiers

PMID36249991
PMCPMC9549752

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.