Evidence map›Paper›PMID 36249889›Full record

ReviewTherapeutic advances in urology

A review of artificial intelligence in prostate cancer detection on imaging.

Indrani Bhattacharya, Yash S Khandwala, Sulaiman Vesal, Wei Shao, Qianye Yang, Simon J C Soerensen, Richard E Fan, Pejman Ghanouni, Christian A Kunder, James D Brooks and 3 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Therapeutic advances in urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06360523 (ProstateAI - A Prospective Paired Validating Cohort Study to Evaluate an MRI-based Optimized Prostate Cancer Diagnostic Pathway Powered by Artificial Intelligence), which is not on this map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06360523 narecruitingnot on this map

ProstateAI - A Prospective Paired Validating Cohort Study to Evaluate an MRI-based Optimized Prostate Cancer Diagnostic Pathway Powered by Artificial Intelligence

TypeinterventionalSponsorChinese University of Hong KongRan2024 to 2028Enrolled368ConditionsProstate CancerArmsAI modal, Standard review
3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Indrani BhattacharyaDepartment of Radiology, Stanford University School of Medicine, 1201 Welch Road, Stanford, CA 94305, USA.
Yash S KhandwalaDepartment of Urology, Stanford University School of Medicine, Stanford, CA, USA.
Sulaiman VesalDepartment of Urology, Stanford University School of Medicine, Stanford, CA, USA.
Wei ShaoDepartment of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Qianye YangCentre for Medical Image Computing, University College London, London, UK.
Simon J C SoerensenDepartment of Urology, Stanford University School of Medicine, Stanford, CA, USA.
Richard E FanDepartment of Urology, Stanford University School of Medicine, Stanford, CA, USA.
Pejman GhanouniDepartment of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Christian A KunderDepartment of Pathology, Stanford University School of Medicine, Stanford, CA, USA.
James D BrooksDepartment of Urology, Stanford University School of Medicine, Stanford, CA, USA.
Yipeng HuCentre for Medical Image Computing, University College London, London, UK.
Mirabela RusuDepartment of Radiology, Stanford University School of Medicine, Stanford, CA, USA.
Geoffrey A SonnDepartment of Radiology, Stanford University School of Medicine, Stanford, CA, USA.ORCID https://orcid.org/0000-0002-0850-1956

Funding

Stanford Molecular and Cellular Characterization LaboratoryU01CA196387 · NCI · STANFORD UNIVERSITY · PI BROOKS, JAMES D. · 2015 to 2020
$5.2M
Rad-pathomic deep learning models to assist radiologists in differentiating aggressive from indolent prostate cancer on MRIR37CA260346 · NCI · STANFORD UNIVERSITY · PI Mirabela Rusu · 2022 to 2026
$2.8M
Cancer Research UK 31378NCI NIH HHS R37 CA260346NCI NIH HHS U01 CA196387
6 · The paper itself

Abstract

A multitude of studies have explored the role of artificial intelligence (AI) in providing diagnostic support to radiologists, pathologists, and urologists in prostate cancer detection, risk-stratification, and management. This review provides a comprehensive overview of relevant literature regarding the use of AI models in (1) detecting prostate cancer on radiology images (magnetic resonance and ultrasound imaging), (2) detecting prostate cancer on histopathology images of prostate biopsy tissue, and (3) assisting in supporting tasks for prostate cancer detection (prostate gland segmentation, MRI-histopathology registration, MRI-ultrasound registration). We discuss both the potential of these AI models to assist in the clinical workflow of prostate cancer diagnosis, as well as the current limitations including variability in training data sets, algorithms, and evaluation criteria. We also discuss ongoing challenges and what is needed to bridge the gap between academic research on AI for prostate cancer and commercial solutions that improve routine clinical care.

Indexed as

artificial intelligencehistopathology imagesmagnetic resonance imagingprostate cancer diagnosisregistrationultrasound images

Identifiers

PMID36249889
PMCPMC9554123

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.