Evidence map›Paper›PMID 36249819›Full record

ArticleFrontiers in pharmacology2022

Acute, chronic, and genotoxic studies on the protopine total alkaloids of the

Zhen Dong, Shu-Sheng Tang, Xiao-Lan Ma, Bin Tan, Zhao-Shan Tang, Chang-Hong Li, Zi-Hui Yang, Jian-Guo Zeng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Frontiers in veterinary science · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Safety and efficacy of a feed additive consisting ofEFSA journal. European Food Safety Authority · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Zhen DongCollege of Veterinary Medicine, Hunan Agricultural University, Changsha, China.
Shu-Sheng TangCollege of Veterinary Medicine, China Agricultural University, Beijing, China.
Xiao-Lan MaCollege of Veterinary Medicine, Shanxi Agricultural University, Jinzhong, China.
Bin TanCollege of Veterinary Medicine, Hunan Agricultural University, Changsha, China.
Zhao-Shan TangHunan MICOLTA Biological Resources Co.,Ltd, Changsha, China.
Chang-Hong LiHunan MICOLTA Biological Resources Co.,Ltd, Changsha, China.
Zi-Hui YangCollege of Veterinary Medicine, Hunan Agricultural University, Changsha, China.
Jian-Guo ZengCollege of Veterinary Medicine, Hunan Agricultural University, Changsha, China.
Hunan Agricultural University · CNChina Agricultural University · CNShanxi Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The protopine alkaloids are widely distributed within the opium poppy family and have a wide range of pharmacological effects. MPTA is a product of the protopine total alkaloids extracted from the

Indexed as

acute toxicitychronic toxicityembryonic developmental toxicityMacleaya cordata (willd.) R. Br.mutagenicityprotopine alkaloidsreproductive toxicityteratogenicity

Identifiers

PMID36249819
PMCPMC9554591
OpenAlexW4297545256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.