Evidence map›Paper›PMID 36249816›Full record

ArticleFrontiers in pharmacology2022

Study and exploration of the pharmacokinetics of traditional Tibetan medicine Ruyi Zhenbao tablets after single and long-term administration.

Hongping Hou, Tengfei Chen, Ziying Xu, Zihui Yu, Caixia Wang, Rongxia Liu, Bo Peng, Wei Yang, Feng Li, Xiangyi Che and 6 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hongping HouInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Tengfei ChenInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Ziying XuCapital Institute of Pediatrics, Beijing, China.
Zihui YuCapital Institute of Pediatrics, Beijing, China.
Caixia WangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Rongxia LiuSchool of Pharmacy, Yantai University, Yantai, China.
Bo PengInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Wei YangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Feng LiGansu Cheezheng Tibetan Medicine Co., Ltd., Beijing, China.
Xiangyi CheGansu Cheezheng Tibetan Medicine Co., Ltd., Beijing, China.
Bing LiYantai Saipute Analyzing Service Co., Ltd., Yantai, China.
Yu WangYantai Saipute Analyzing Service Co., Ltd., Yantai, China.
Ling SongInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Yunhang GaoInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Zuguang YeInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.
Guangping ZhangInstitute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tibetan medicine is one of the oldest traditional medicine systems in the world. Taking the Ruyi Zhenbao tablet (RYZB) as an example, which is a widely used classic oral Tibetan medicine, this article discusses the pharmacokinetics of single administration and long-term treatment and analyzed its metabolic properties and tissue distribution

Indexed as

long-term administrationpharmacokineticsRuyi Zhenbao tabletsingle administrationTibetan medicine

Identifiers

PMID36249816
PMCPMC9559938

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.