Evidence map›Paper›PMID 36249611›Full record

ArticleCureus2022

COVID-19 and Sepsis in an Atypical Case of Mixed Connective Tissue Disorder Presenting With a Myasthenic Crisis.

Lav Kumar Shah, Biswas Pant, Nashruva Mony, Sumitanand Mishra, Januka Gaire, Sandesh Sharma

Abstract readCase Reports
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lav Kumar ShahSurgery, Patan Academy of Health Sciences, Lalitpur, NPL.
Biswas PantMedicine, Patan Academy of Health Sciences, Lalitpur, NPL.
Nashruva MonyMedicine, Nepal Korea Friendship Municipality Hospital, Bhaktapur, NPL.
Sumitanand MishraRadiology, Himal Hospital, Kathmandu, NPL.
Januka GaireInternal Medicine, Nepal Bal Tatha Mahila Prasuti Sewa Polyclinic Pvt. Ltd., Birendranagar, NPL.
Sandesh SharmaInternal Medicine, Kaushallya Memorial Hospital Pvt. Ltd., Banke, NPL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myasthenia gravis (MG) is an autoimmune illness that causes neuromuscular junctions to be damaged by anti-acetylcholine receptor antibodies. It is a very rare condition that is more common among women. Fatigable fluctuating diplopia or ptosis is the characteristic early appearance of this condition. Dysphagia or dysphonia may be present in rare cases. This illness can affect any group of skeletal muscles, including those in the neck and upper limbs. It can also affect the muscles that help you breathe, which can lead to breathing failure. We present a case of a 20-year-old female diagnosed with mixed connective tissue disease presenting with acute respiratory failure as the initial presentation of MG. Clinicians have to have a high index of suspicion for myasthenia when patients arrive with fatigable muscle weakness. This will cut down on the amount of money spent on investigations and the risk of morbidity.

Indexed as

acute polymyositiscovid-19mixed connective tissue diseasemyasthenic crisisneuromuscular junctionsystemic lupus erythemasystemic scleroderma

Identifiers

PMID36249611
PMCPMC9556605

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.