Evidence map›Paper›PMID 36249526›Full record

ArticlePsychiatry journal2022

The Effects of Citalopram and Thalamic Dopamine D

Todd Zorick, Kyoji Okita, K Brooke Renard, Mark A Mandelkern, Arthur L Brody, Edythe D London

Open access · hybridAbstract read
In one paragraph

Article in Psychiatry journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. The Association of Antidepressant Use and Impulse Control Disorder in Parkinson's Disease.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024
    Observational
  7. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
    Article
  8. Observational
  9. Severe alcohol use disorder after initiation of selective serotonin reuptake inhibitor therapy.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 2 countries.

Todd ZorickDepartment of Psychiatry and Biobehavioral Sciences, UCLA, USA.ORCID https://orcid.org/0000-0002-5851-785X
Kyoji OkitaIntegrative Brain Imaging Center, Japanese National Center of Neurology and Psychiatry, Japan.ORCID https://orcid.org/0000-0002-7189-9039
K Brooke RenardCalifornia University of Science and Medicine, USA.
Mark A MandelkernDept. of Physics, University of California, Irvine, USA.ORCID https://orcid.org/0000-0002-1189-2775
Arthur L BrodyDept. of Psychiatry, UCSD/VA San Diego, USA.ORCID https://orcid.org/0000-0003-2614-8495
Edythe D LondonDepartment of Psychiatry and Biobehavioral Sciences, UCLA, USA.
National Center of Neurology and Psychiatry · JPNeurobehavioral Systems · USUCLA Medical Center · USUniversity of California, Irvine · USUniversity of California San Diego · USUniversity of California System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed for patients who misuse alcohol, especially in the context of comorbid depressive symptoms. Deficits in impulse control and decision-making are linked to routine alcohol consumption and alcohol dependence. The goal of this study was to determine the effects of a single dose of citalopram on measures of impulsivity, decision-making, and/or brain dopamine receptor availability in alcohol-dependent individuals. A double-blind, placebo-controlled, within-subject, outpatient study was conducted with active alcohol-dependent (DSM-IV-TR criteria) participants (

Identifiers

PMID36249526
PMCPMC9553840
OpenAlexW4296783498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.