Evidence map›Paper›PMID 36249455›Full record

ReviewAvicenna journal of phytomedicine

Meticulous parade on naringin respecting its pharmacological activities and novel formulations.

Mahboob Alam, Farogh Ahsan, Tarique Mahmood, Arshiya Shamim, Saba Parveen, Mohammad Shariq, Vaseem Ahmad Ansari

Open access · greenAbstract readReview
In one paragraph

Review in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mahboob AlamDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Kursi Road, Lucknow, India.
Farogh AhsanDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Kursi Road, Lucknow, India.
Tarique MahmoodDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Kursi Road, Lucknow, India.
Arshiya ShamimDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Kursi Road, Lucknow, India.
Saba ParveenDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Kursi Road, Lucknow, India.
Mohammad ShariqDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Kursi Road, Lucknow, India.
Vaseem Ahmad AnsariDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Kursi Road, Lucknow, India.
Integral University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Medicinal plants having antioxidant potential possess numerous constituents which are responsible for different beneficial effects and are used as an alternative resource of medicine to lessen diseases linked with oxidative stress. Flavonoids are identified in the plants since ages and display wide spectrum of biological actions that might be able to stimulate the steps which are disturbed in different diseases. Flavonoids are significant natural compounds with various biologic properties, among which the most common is the anti-oxidant potential. Citrus flavonoids establish an important stream of flavonoids. Naringin, very common flavonoids present in the diet, belongs to the family of flavanone. It is the principal constituent of citrus family that contains flavonoids for example tomatoes, grapefruits and oranges. Materials and Methods: In this article, we reviewed naringin with respect to sources, chemical property, pharmacokinetics, pharmacological activity, and novel formulations. The literature survey has been done by searching different databases such as Psyc INFO, Science Direct, PubMed, EMBASE, Google, Google Scholar, Medline. Results: Naringin is known to behave as an antioxidant and possess anti-inflammatory, anti-apoptotic, anti-atherosclerotic, neuroprotective, anti-psychotic, anti-asthmatic, anti-diabetic, hepatoprotective, anti-tussive, cardioprotective, and anti-obesity activity. Further clinical studies using large sample sizes remain essential to obtain the appropriate dose and form of naringin for averting diseases. Furthermore, the therapeutic approach of these bioflavonoids is significantly inappropriate due to the lack of clinical evidence. Different plants must be explored further to find these bioflavonoids in them. Conclusion: The results of this exploration provides biological actions of bioflavonoid (naringin), predominantly on pharmacological and novel dosage forms of naringin.

Indexed as

FlavonoidsFormulationsNaringinPharmacokinetics Pharmacological activity

Identifiers

PMID36249455
PMCPMC9516400
OpenAlexW4306667373

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.