Evidence map›Paper›PMID 36249300›Full record

ArticleOphthalmology science2021

Distribution of Choroidal Thickness and Choroidal Vessel Dilation in Healthy Japanese Individuals: The Nagahama Study.

Yuki Mori, Masahiro Miyake, Yoshikatsu Hosoda, Akihito Uji, Eri Nakano, Ayako Takahashi, Yuki Muraoka, Manabu Miyata, Hiroshi Tamura, Sotaro Ooto and 5 more

Open access · goldAbstract read
In one paragraph

Article in Ophthalmology science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Global choroidal thickness in healthy eyes assessed by ultra-widefield swept-source optical coherence tomography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Article
  7. Article
  8. Observational
  9. Article
  10. Observational
  11. Choroidal Features of Cynomolgus Macaques in Relation to Age and Axial Length.Investigative ophthalmology & visual science · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Correlation between choroidal thickness and the degree of myopia.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Yuki MoriDepartment of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Masahiro MiyakeDepartment of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yoshikatsu HosodaDepartment of Ophthalmology, Osaka Red-Cross Hospital, Osaka, Japan.
Akihito UjiDepartment of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Eri NakanoDepartment of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Ayako TakahashiDepartment of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yuki MuraokaDepartment of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Manabu MiyataDepartment of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hiroshi TamuraDepartment of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Sotaro OotoDepartment of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Yasuharu TabaraCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Kenji YamashiroDepartment of Ophthalmology, Otsu Red-Cross Hospital, Otsu, Japan.
Fumihiko MatsudaCenter for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Akitaka TsujikawaDepartment of Ophthalmology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Nagahama Study Group
Kyoto University · JPOsaka Red Cross Hospital · JPOtsu Red Cross Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report fundamental epidemiologic data for choroidal parameters such as choroidal thickness and index of choroidal vascularity in Japanese individuals and to evaluate their correlations with age, sex, systemic parameters, and other ocular parameters. Design: Population-based cohort study. Participants: A total of 9850 individuals participated in the first follow-up of the Nagahama Prospective Cohort for Comprehensive Human Bioscience (the Nagahama Study) conducted between 2013 and 2016. Methods: All participants underwent standardized ophthalmic examinations, including OCT with enhanced depth imaging (EDI; RS-3000 Advance; Nidek). We manually segmented the choroidoscleral interface to measure subfoveal choroidal thickness (SFCT) and calculated the normalized choroidal intensity obtained with EDI (NCI Main Outcome Measures: Distribution of SFCT, NCI Results: Age-sex standardized SFCT, NCI Conclusions: We report normative Japanese SFCT, NCI

Indexed as

AL, axial lengthAMD, age-related macular degenerationChoroidal epidemiologyChoroidal intensityCSC, central serous chorioretinopathyCVI, choroidal vascularity indexEDI, enhanced depth imagingFCT, parafoveal choroidal thicknessIOP, intraocular pressureNagahama StudyNCIEDI, normalized choroidal intensity obtained with enhanced depth imagingNCI, normalized choroidal intensityNFL, nerve fiber layerOCTOCT, optical coherence tomographySEEDS, Singapore Epidemiology of Eye Diseases StudySE, spherical equivalentSFCT, subfoveal choroidal thicknessSubfoveal choroidal thickness

Identifiers

PMID36249300
PMCPMC9562294
OpenAlexW3172189454

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.