Evidence map›Paper›PMID 36249271›Full record

ArticleEnvironmental epidemiology (Philadelphia, Pa.)2022

Epigenome-wide association of neonatal methylation and trimester-specific prenatal PM

Milan N Parikh, Cole Brokamp, Erika Rasnick, Lili Ding, Tesfaye B Mersha, Katherine Bowers, Alonzo T Folger

Open access · goldAbstract read
In one paragraph

Article in Environmental epidemiology (Philadelphia, Pa.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Prenatal PMNature communications · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Prenatal black carbon exposure and DNA methylation in umbilical cord blood.International journal of hygiene and environmental health · 2025
    Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 4 countries.

Milan N ParikhDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID https://orcid.org/0000-0002-8549-3873
Cole BrokampDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID https://orcid.org/0000-0002-0289-3151
Erika RasnickDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID https://orcid.org/0000-0002-7150-5845
Lili DingDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID https://orcid.org/0000-0003-2345-3726
Tesfaye B MershaDepartment of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio.ORCID https://orcid.org/0000-0002-9189-8447
Katherine BowersDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID https://orcid.org/0000-0001-6711-4334
Alonzo T FolgerDivision of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.ORCID https://orcid.org/0000-0002-0849-723X
Cincinnati Children's Hospital Medical Center · US

Funding

Unraveling ancestry and environmental exposure interactions in childhood asthmaR01HL132344 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI MERSHA, TESFAYE B. · 2016 to 2020
$3.4M
Epigenome-wide variations and socio-environmental exposures in African American asthmatic childrenR01HG011411 · NHGRI · CINCINNATI CHILDRENS HOSP MED CTR · PI MERSHA, TESFAYE B. · 2021 to 2025
$3.4M
A Framework for Automated and Reproducible Geomarker Curation and Computation at ScaleR01LM013222 · NLM · CINCINNATI CHILDRENS HOSP MED CTR · PI BROKAMP, COLE · 2020 to 2023
$1.4M
NHGRI NIH HHS R01 HG011411NHLBI NIH HHS R01 HL132344NLM NIH HHS R01 LM013222
6 · The paper itself

Abstract

Exposure to particulate matter with an aerodynamic diameter smaller than 2.5 microns (PM Methods: After collecting salivary samples from a cohort of 91 neonates, DNAm was assessed at over 850,000 cytosine-guanine dinucleotide (CpG) methylation sites on the epigenome using the MethylationEPIC array. Daily ambient PM Results: Our analysis showed that cg18705808 was associated with the combined average of PM Conclusions: The differences in pathway and network analyses could potentially indicate trimester-specific effects of PM

Indexed as

DNA methylationFine particulate matterPrenatal exposure

Identifiers

PMID36249271
PMCPMC9556110
OpenAlexW4300772732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.