Evidence map›Paper›PMID 36249210›Full record

ArticleFrontiers in public health2022

Application of oXiris-continuous hemofiltration adsorption in patients with sepsis and septic shock: A single-centre experience in China.

Yanyan Zhou, Chenfang Wu, Lin Ouyang, Ying Peng, Dingming Zhong, Xiaohong Xiang, Jinxiu Li

Abstract read
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Association of oXirisJournal of personalized medicine · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Macrophage activation syndrome in Sepsis: from pathogenesis to clinical management.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yanyan ZhouDepartment of Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Chenfang WuDepartment of Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Lin OuyangDepartment of Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Ying PengDepartment of Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Dingming ZhongDepartment of Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Xiaohong XiangDepartment of Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.
Jinxiu LiDepartment of Critical Care Medicine, The Second Xiangya Hospital of Central South University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

oXiris is a new, high-adsorption membrane filter in continuous hemofiltration adsorption to reduce the inflammatory response in sepsis. The investigators retrospectively reviewed patients with sepsis/septic shock who underwent at least one oXiris-treatment from November 2020 to March 2022. The demographic data, baseline levels before treatment, clinical datas, prognosis, and the occurrence of adverse events during treatment were recorded. 90 patients were enrolled in this study. The hemodynamic indices, sequential organ failure assessment score, lactate, inflammatory biomarkers levels were significantly improved at 12 h and 24 h after treatment. Procalcitonin and interleukin-6 reduction post-treatment of oXiris were most pronounced in infection from skin and soft tissue, urinary and abdominal cavity. Logistic regression analysis showed that pre-treatment sequential organ failure assessment score (

Indexed as

HemofiltrationSepsisShock, SepticAdsorptionBiomarkersChinaHumansInterleukin-6Lactic AcidProcalcitoninRetrospective StudiesBiomarkersInterleukin-6Lactic AcidProcalcitonincontinuous hemofiltration adsorptioncytokine stormoXirissepsisseptic shock

Identifiers

PMID36249210
PMCPMC9557776

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.