Evidence map›Paper›PMID 36249085›Full record

ArticleLaryngoscope investigative otolaryngology2022

Mucormycosis in pre-COVID-19 and COVID-19 era: A study of prevalence, risk factors and clinical features.

Parisa Arjmand, Milad Bahrami, Zahra Eslami Mohammadie, Mohammadhossein Taherynejad, Negar Yeganeh Khorasani, Hassan Mehrad-Majd, Imaneh Roshanzamir, Mehdi Bakhshaee

Open access · goldAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A 17-year-old student with ankle sprain to leg amputation.Journal of surgical case reports · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Parisa ArjmandDepartment of Otorhinolaryngology, Ghaem Hospital Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0001-5580-3087
Milad BahramiDepartment of Laboratory Sciences, Faculty of Paramedical Sciences Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0001-9743-1007
Zahra Eslami MohammadieFaculty of Paramedical Sciences Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0002-7724-5933
Mohammadhossein TaherynejadFaculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0001-9583-1357
Negar Yeganeh KhorasaniFaculty of Pharmacy Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0003-1230-6827
Hassan Mehrad-MajdCancer Molecular Pathology Research Center Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0002-8745-6558
Imaneh RoshanzamirSinus and Surgical Endoscopic Research Center, Department of Otorhinolaryngology Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0003-4437-9940
Mehdi BakhshaeeSinus and Surgical Endoscopic Research Center, Department of Otorhinolaryngology Mashhad University of Medical Sciences Mashhad Iran.ORCID https://orcid.org/0000-0001-9590-4798
Mashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Mucormycosis is a rare yet devastating fungal disease with a frequently fatal outcome. The purpose of this study was to compare the prevalence of mucormycosis, evaluate its risk factors, and assess the patients' outcomes in pre-COVID-19 and COVID-19 era. Methods: In this retrospective observational study, clinical data of 158 patients with confirmed histopathological diagnosis of mucormycosis were collected from the medical records departments of Imam Reza and Ghaem hospitals, Mashhad, Iran during 2018-2021. The collected data were risk factors associated with mucormycosis including age, gender, underlying diseases, details of corticosteroid administration, and complications such as blindness and mortality. Results: Of 158 studied patients, 48 patients were diagnosed in the pre-pandemic period whereas 110 cases were admitted during the pandemic era. COVID-19 associated mucormycosis (CAM) was observed in 58.1% of the pandemic cases. In the pre-pandemic period, cancer (89.5% vs. 39%, Conclusion: The COVID-19 pandemic has led to an increased prevalence of mucormycosis, due to the convergence of interlinked risk factors such as diabetes mellitus, corticosteroid therapy, and COVID-19. Therefore, clinicians must be aware of the probable occurrence of mucormycosis in the first or second week of COVID-19 infection in vulnerable patients and use the steroids cautiously. Level of evidence: 4 Laryngoscope Investigative Otolaryngology, 2022.

Indexed as

black fungusCOVID‐19mucormycosisrisk factorsSARS‐CoV‐2

Identifiers

PMID36249085
PMCPMC9539365
OpenAlexW4294867844

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.