Evidence map›Paper›PMID 36248960›Full record

ReviewFrontiers in oncology2022

Molecular biology of pancreatic neuroendocrine tumors: From mechanism to translation.

Xiaofei Shen, Xingzhou Wang, Xiaofeng Lu, Yang Zhao, Wenxian Guan

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Xiaofei ShenDepartment of General Surgery, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Xingzhou WangDepartment of General Surgery, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Xiaofeng LuDepartment of General Surgery, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Yang ZhaoState Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Wenxian GuanDepartment of General Surgery, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China.
Nanjing Drum Tower Hospital · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic neuroendocrine tumors (pNETs) are a group of heterogeneous tumors originated from progenitor cells. As these tumors are predominantly non-functional, most of them display asymptomatic characteristics, making it difficult to be realized from early onset. Therefore, patients with pNETs are usually diagnosed with metastatic disease or at a late disease stage. The relatively low incidence also limits our understanding of the biological background of pNETs, which largely impair the development of new effective drugs. The fact that up to 10% of pNETs develop in patients with genetic syndromes have promoted researchers to focus on the gene mutations and driver mutations in

Indexed as

epigenetic modulationmolecular biologypancreatic neuroendocrine tumors (pancreatic NETs)signaling pathwaytargeted therapies

Identifiers

PMID36248960
PMCPMC9554633
OpenAlexW4297548975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.