ReviewFrontiers in immunology2022
Oral manifestations serve as potential signs of ulcerative colitis: A review.
Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
- Elevated periodontal disease risk in ulcerative colitis patients: evidence from a comparative case-control study.Odontology · 2026Article
- Unlocking Potential ofGels (Basel, Switzerland) · 2026Article
- Successful Remission of Refractory Oral Ulcers Treated with Low-Dose Thalidomide and Colchicine: A Case Report.Reports (MDPI) · 2026Article
- Case Report: Exploring the link between severe gingivitis and inflammatory bowel disease in a young patient.Frontiers in dental medicine · 2026Article
- Patient with Inflammatory Bowel Disease in a Dental Office-Which Antibiotic to Choose?-Narrative Review.Journal of clinical medicine · 2025Review
- Systemic Consequences of Inflammatory Bowel Disease Beyond Immune-Mediated Manifestations.Journal of clinical medicine · 2025Review
- Prevalence and Severity of Periodontitis in Patients with Ulcerative Colitis: A Case-Control Study.International journal of environmental research and public health · 2025Article
- Article
- Shared immune-inflammatory mechanisms between ulcerative colitis and periodontitis: a multi-omics analysis.Frontiers in immunology · 2025Article
- Dental problems and oral microbiome alterations in ulcerative colitis.Frontiers in immunology · 2025Review
- OralFrontiers in cellular and infection microbiology · 2025Review
- Oral manifestations associated with gastrointestinal diseases - A review.Bioinformation · 2025Article
- Oral mucosal findings in ambulatory patients with inflammatory bowel disease.Brazilian oral research · 2025Article
- Regulation of ulcerative colitis progression by ferroptosis pathway genes: HSP90AA1, SNCA, TLR4, and PTGS2.American journal of translational research · 2025Article
- Association of oral manifestations with severity of the disease in ulcerative colitis patients.BMC gastroenterology · 2024Article
- Dehydroevodiamine Alleviates Ulcerative Colitis by Inhibiting the PI3K/AKT/NF-κB Signaling Pathway via Targeting AKT1 and Regulating Gut Microbes and Serum Metabolism.Molecules (Basel, Switzerland) · 2024Article
- Lower fecal microbiota transplantation ameliorates ulcerative colitis by eliminating oral-derived Fusobacterium nucleatum and virulence factor.Gut pathogens · 2024Article
- The Potential Teeth Bleaching and Halitosis Prevention Effects ofJournal of functional biomaterials · 2024Article
- HIV-Related Oral Mucosa Lesions: A Cross-Sectional Study on a Cohort of Italian Patients.Biomedicines · 2024Article
- Evaluating the significance of ECSCR in the diagnosis of ulcerative colitis and drug efficacy assessment.Frontiers in immunology · 2024Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As an immune dysregulation-related disease, although ulcerative colitis (UC) primarily affects the intestinal tract, extraintestinal manifestations of the disease are evident, particularly in the oral cavity. Herein, we have reviewed the various oral presentations, potential pathogenesis, and treatment of oral lesions related to UC. The oral manifestations of UC include specific and nonspecific manifestations, with the former including pyostomatitis vegetans and the latter encompassing recurrent aphthous ulcers, atrophic glossitis, burning mouth syndrome, angular cheilitis, dry mouth, taste change, halitosis, and periodontitis. Although the aetiology of UC has not been fully determined, the factors leading to its development include immune system dysregulation, dysbiosis, and malnutrition. The principle of treating oral lesions in UC is to relieve pain, accelerate the healing of lesions, and prevent secondary infection, and the primary procedure is to control intestinal diseases. Systemic corticosteroids are the preferred treatment options, besides, topical and systemic administration combined with dietary guidance can also be applied. Oral manifestations of UC might accompany or precede the diagnosis of UC, albeit with the absence of intestinal symptoms; therefore, oral lesions, especially pyostomatitis vegetans, recurrent aphthous ulcer and periodontitis, could be used as good mucocutaneous signs to judge the occurrence and severity of UC, thus facilitating the early diagnosis and treatment of UC and avoiding severe consequences, such as colon cancer.
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