Evidence map›Paper›PMID 36248781›Full record

ArticleFrontiers in immunology2022

Preoperative systemic inflammatory response index predicts long-term outcomes in type B aortic dissection after endovascular repair.

Yufei Zhao, Xiang Hong, Xinsheng Xie, Daqiao Guo, Bin Chen, Weiguo Fu, Lixin Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yufei ZhaoDepartment of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Xiang HongDepartment of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Xinsheng XieDepartment of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Daqiao GuoDepartment of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Bin ChenDepartment of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Weiguo FuDepartment of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Lixin WangDepartment of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhongshan Hospital of Xiamen University · CNZhongshan Hospital · CNFudan University · CNNational Clinical Research Center for Digestive Diseases · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Inflammation is a hallmark of the initial development and progression of aortic dissection. This study aimed to investigate the value of preoperative inflammatory biomarkers in predicting aorta-related adverse events (AAEs) after thoracic endovascular aortic repair (TEVAR) for type B aortic dissection. Methods: We included all patients who underwent TEVAR for type B aortic dissection between November 2016 and November 2020 in this single-center, retrospective cohort study. Patients were divided into two groups: the AAEs group (n = 75) and the non-AAEs group (n = 126). Preoperative inflammatory biomarkers were recorded, including neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), systemic immune inflammation index (SII), and systemic inflammatory response index (SIRI). Patients were followed-up for the development of AAEs. Prediction accuracy of inflammatory biomarkers for AAEs were evaluated using the area under the receiver operating characteristic curves. Results: This study included 201 patients, of whom 80.0% were men, with a mean age of 59.1 ± 12.5 years. A total of 75 patients developed AAEs after TEVAR. The AUCs of NLR, MLR, PLR, SII, and SIRI for AAEs were.746,.782,.534,.625 and.807, respectively. Age and SIRI were independent risk factors for the AAEs after TEVAR (HR 3.264, p <.001; HR 4.281, p <.001, respectively). Survival analysis revealed significantly lower AAE-free status in patients with preoperative SIRI > = 4 (p <.001). Conclusion: Increased preoperative SIRI and age are independent risk factors for AAEs after TEVAR in type B aortic dissection.

Indexed as

Aortic Aneurysm, ThoracicAortic DissectionEndovascular ProceduresAgedFemaleHumansInflammationMaleMiddle AgedRetrospective StudiesSystemic Inflammatory Response Syndromebiomarkerssystemic immune inflammation index (SII)systemic inflammatory response index (SIRI)thoracic endovascular aortic repairtype B aortic dissection

Identifiers

PMID36248781
PMCPMC9554789
OpenAlexW4297491803

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.