Evidence map›Paper›PMID 36248729›Full record

ArticleiScience2022

Antibacterial and anti-inflammatory properties of host defense peptides against

Leonardo Cecotto, Kok van Kessel, Margreet A Wolfert, Charles Vogely, Bart van der Wal, Harrie Weinans, Jos van Strijp, Saber Amin Yavari

Open access · goldAbstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Macrophage adaptation to hypoxia: metabolism, migration, and phagocytosis.Frontiers in cellular and infection microbiology · 2025
    Article
  3. Review
  4. Article
  5. Evaluation of silver bio-functionality in a multicellularFrontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Leonardo CecottoDepartment of Orthopedics, University Medical Center Utrecht, 3508GA Utrecht, the Netherlands.
Kok van KesselDepartment of Medical Microbiology, University Medical Center Utrecht, 3508GA Utrecht, the Netherlands.
Margreet A WolfertDepartment of Chemical Biology and Drug Discovery, Utrecht University, 3508GA Utrecht, the Netherlands.
Charles VogelyDepartment of Orthopedics, University Medical Center Utrecht, 3508GA Utrecht, the Netherlands.
Bart van der WalDepartment of Orthopedics, University Medical Center Utrecht, 3508GA Utrecht, the Netherlands.
Harrie WeinansDepartment of Orthopedics, University Medical Center Utrecht, 3508GA Utrecht, the Netherlands.
Jos van StrijpDepartment of Medical Microbiology, University Medical Center Utrecht, 3508GA Utrecht, the Netherlands.
Saber Amin YavariDepartment of Orthopedics, University Medical Center Utrecht, 3508GA Utrecht, the Netherlands.
University Medical Center Utrecht · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cationic host defense peptides (HDPs) are a promising alternative to antibiotics in the fight against

Indexed as

ImmunologyMicrobiology

Identifiers

PMID36248729
PMCPMC9563556
OpenAlexW4296935226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.