ArticleFrontiers in human neuroscience2022
The functional connectivity of the basal ganglia subregions changed in mid-aged and young males with chronic prostatitis/chronic pelvic pain syndrome.
Article in Frontiers in human neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Progress in the research of artificial intelligence in andrology: a narrative review.Translational andrology and urology · 2026Review
- Artificial Intelligence in the Assessment of Males with Chronic Pelvic Pain Syndrome: An Up-to-Date UPOINTS-Based Narrative Mapping Review.Diagnostics (Basel, Switzerland) · 2026Review
- Research progress of extracellular vesicles in the pathogenesis of type IIIA chronic prostatitis.Frontiers in immunology · 2025Review
- Efficacy and brain modulation mechanisms of acupuncture for chronic prostatitis/chronic pelvic pain syndrome revealed by structural MRI changes.Frontiers in neurology · 2025Article
- Abnormal Functional Connectivity Intra- and Inter-Network in Resting-State Brain Networks of Patients with Toothache.Journal of pain research · 2024Article
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
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Abstract
Background: The Basal ganglia (BG) played a crucial role in the brain-level mechanisms of chronic pain disorders. However, the functional changes of BG in chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) are still poorly understood. This study investigated the BG subregions' resting-state functional connectivity (rs-FC) in CP/CPPS patients compared with healthy controls. Methods: Twenty eight patients with CP/CPPS and 28 age- and education-matched healthy males underwent clinical measurements and 3T brain MR imaging, including T1-weighted structural images and resting-state functional imaging. The data were analyzed by the seeded-based rs-FC analysis. Then, a machine learning method was applied to assess the feasibility of detecting CP/CPPS patients through the changed rs-FC. Results: Compared with healthy males, patients presented decreased rs-FC between the BG subregions and right middle cingulate cortex, and correlated with pain ( Conclusion: These findings provide evidence of altered BG subregions' rs-FC in CP/CPPS, which may contribute to our understanding of the BG's role in CP/CPPS.
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