Evidence map›Paper›PMID 36248677›Full record

ArticleEcology and evolution2022

The interplay between prior selection, mild intermittent exposure, and acute severe exposure in phenotypic and transcriptional response to hypoxia.

Millicent N Ekwudo, Morad C Malek, Cora E Anderson, Lev Y Yampolsky

Open access · goldAbstract read
In one paragraph

Article in Ecology and evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Role ofInternational journal of molecular sciences · 2024
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Millicent N EkwudoDepartment of Biological Sciences East Tennessee State University Johnson City Tennessee USA.
Morad C MalekDepartment of Biological Sciences East Tennessee State University Johnson City Tennessee USA.
Cora E AndersonDepartment of Biological Sciences East Tennessee State University Johnson City Tennessee USA.
Lev Y YampolskyDepartment of Biological Sciences East Tennessee State University Johnson City Tennessee USA.ORCID https://orcid.org/0000-0001-7680-6025
East Tennessee State University · USUniversity of Notre Dame · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypoxia has profound and diverse effects on aerobic organisms, disrupting oxidative phosphorylation and activating several protective pathways. Predictions have been made that exposure to mild intermittent hypoxia may be protective against more severe exposure and may extend lifespan. Here we report the lifespan effects of chronic, mild, intermittent hypoxia, and short-term survival in acute severe hypoxia in four clones of

Indexed as

Daphniadifferential gene expressionhypoxialifespanlocal adaptationmitochondrial membrane potentialtolerance

Identifiers

PMID36248677
PMCPMC9548574
OpenAlexW4303983266

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.