Evidence map›Paper›PMID 36248663›Full record

ArticleFrontiers in neuroscience2022

Proteomic and metabolomic profiling of acupuncture for migraine reveals a correlative link via energy metabolism.

Lu Liu, Weizheng Li, Linpeng Wang, Pengyun Gong, Tianli Lyu, Dapeng Liu, Yajie Zhang, Yijie Guo, Xiang Liu, Min Tang and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 13 citations in OpenAlex.

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  11. Modulation of lung CD11bChinese medicine · 2025
    Article
  12. Review
  13. The serum proteomic profile in patients with migraine.Frontiers in molecular neuroscience · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Lu LiuBeijing Key Laboratory of Acupuncture Neuromodulation, Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Weizheng LiSchool of Engineering Medicine & School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
Linpeng WangBeijing Key Laboratory of Acupuncture Neuromodulation, Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Pengyun GongSchool of Engineering Medicine & School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
Tianli LyuBeijing Key Laboratory of Acupuncture Neuromodulation, Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Dapeng LiuThird Affiliated Hospital, Beijing University of Chinese Medicine, Beijing, China.
Yajie ZhangShanxi Hospital of Integrated Traditional and Western Medicine, Taiyuan, China.
Yijie GuoSchool of Engineering Medicine & School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
Xiang LiuSchool of Engineering Medicine & School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
Min TangSchool of Engineering Medicine & School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
Hongke HuSchool of Engineering Medicine & School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
Chao LiuSchool of Engineering Medicine & School of Biological Science and Medical Engineering, Beihang University, Beijing, China.
Bin LiBeijing Key Laboratory of Acupuncture Neuromodulation, Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Ministry of Industry and Information Technology · CNBeihang University · CNBeijing Hospital of Traditional Chinese Medicine · CNCapital Medical University · CNBeijing University of Chinese Medicine · CNShanxi Province Hospital of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Migraine is a neurovascular disease with a high disability rate. Acupuncture treatment has emerged as a safe and viable alternative prophylactic therapy that can effectively alleviate the duration and frequency of migraine attacks. However, the therapeutic mechanisms underlying the effects of acupuncture are yet to be systematically elucidated. In this study, we enrolled female patients with migraine without aura (

Indexed as

acupunctureenergy metabolism pathwaysmetabolomicsmigraineproteomics

Identifiers

PMID36248663
PMCPMC9557737
OpenAlexW4297999990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.