Evidence map›Paper›PMID 36248221›Full record

ArticleCase reports in endocrinology2022

Functional Localization of Adult-Onset Idiopathic Nesidioblastosis.

Jess C Hercus, Pouneh Pasha, Sadiq Al Lawati, Peter Kim, Andre Mattman, Douglas Webber, David M Thompson

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jess C HercusDepartment of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.ORCID https://orcid.org/0000-0002-2703-1806
Pouneh PashaDivision of Internal Medicine, Department of Medicine, University of British Columbia, 5913-1081 Burrard St., Vancouver, British Columbia V6Z 1Y6, Canada.
Sadiq Al LawatiDivision of Endocrinology, Department of Medicine, University of British Columbia, 2775 Laurel Street, 4th Floor, Vancouver, British Columbia V5Z 1M9, Canada.
Peter KimDivision of General Surgery, Department of Medicine, University of British Columbia, 2775 Laurel Street, 11th Floor, Vancouver, British Columbia V5Z 1M9, Canada.
Andre MattmanDivision of Pathology and Laboratory Medicine, Department of Medicine, University of British Columbia, G227-2211 Wesbrook Mall, Vancouver, British Columbia V6T 2B5, Canada.ORCID https://orcid.org/0000-0001-8629-2419
Douglas WebberDivision of Pathology and Laboratory Medicine, Department of Medicine, University of British Columbia, G227-2211 Wesbrook Mall, Vancouver, British Columbia V6T 2B5, Canada.
David M ThompsonDivision of Endocrinology, Department of Medicine, University of British Columbia, 2775 Laurel Street, 4th Floor, Vancouver, British Columbia V5Z 1M9, Canada.ORCID https://orcid.org/0000-0002-8597-2356
University of British Columbia · CASimon Fraser University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nesidioblastosis is a rare pancreatic disorder involving enlarged beta cells throughout the pancreas, causing elevated insulin production. We present the case of a 53-year-old woman with the initial symptom of fasting hypoglycemia. No pancreatic lesions were indicated on computed tomography and magnetic resonance imaging scans, and an octreotide scan was negative for insulinoma. Selective arterial calcium stimulation (SACST) showed increased insulin production from the stimulation of 3 out of 5 arteries. The SACST results suggested a diagnosis of nesidioblastosis, which was confirmed by histopathology after a subtotal distal pancreatectomy. The patient has normal glucose tolerance after surgery with no further problems of hypoglycemia, indicating that this is a rare case of nesidioblastosis extending only partially through the pancreas.

Identifiers

PMID36248221
PMCPMC9568342
OpenAlexW4303457423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.