Evidence map›Paper›PMID 36248187›Full record

ArticleMediators of inflammation2022

Inhibition of CEBPB Attenuates Lupus Nephritis via Regulating Pim-1 Signaling.

Xiaoyang Wang, Weili Cheng, Xiaopan Chen, Yanan Gong, Guangjie Wang, Xiaoxue Zhang, Yuanyuan Qi

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  8. Article
  9. Damage-Associated Molecular Patterns and Pattern Recognition Receptors in the Podocyte.Journal of the American Society of Nephrology : JASN · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaoyang WangDepartment of Nephrology, The First Affiliated Hospital of Zhengzhou University, 1#, Jianshe East Road, Zhengzhou, 450052 Henan, China.ORCID https://orcid.org/0000-0002-2770-5268
Weili ChengDepartment of Nephrology, The First Affiliated Hospital of Zhengzhou University, 1#, Jianshe East Road, Zhengzhou, 450052 Henan, China.ORCID https://orcid.org/0000-0001-5440-6266
Xiaopan ChenDepartment of Nephrology, The First Affiliated Hospital of Zhengzhou University, 1#, Jianshe East Road, Zhengzhou, 450052 Henan, China.ORCID https://orcid.org/0000-0002-1753-4434
Yanan GongDepartment of Nephrology, The First Affiliated Hospital of Zhengzhou University, 1#, Jianshe East Road, Zhengzhou, 450052 Henan, China.ORCID https://orcid.org/0000-0002-6700-2399
Guangjie WangDepartment of Obstetrics and Gynecology, Third Affiliated Hospital of Henan University of Traditional Chinese Medicine, 63#, Dongming Road, Zhengzhou, 450003 Henan, China.ORCID https://orcid.org/0000-0002-8734-1638
Xiaoxue ZhangDepartment of Nephrology, The First Affiliated Hospital of Zhengzhou University, 1#, Jianshe East Road, Zhengzhou, 450052 Henan, China.ORCID https://orcid.org/0000-0002-2410-5865
Yuanyuan QiDepartment of Nephrology, The First Affiliated Hospital of Zhengzhou University, 1#, Jianshe East Road, Zhengzhou, 450052 Henan, China.ORCID https://orcid.org/0000-0002-5872-3311
First Affiliated Hospital of Zhengzhou University · CNHenan University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease leading to inflammatory damage in multiple target organs, and lupus nephritis (LN) is one of the most life-threatening organ manifestations. CCAAT/enhancer-binding protein

Indexed as

Lupus Erythematosus, SystemicLupus NephritisAdenosine TriphosphateAnimalsCCAAT-Enhancer-Binding Protein-betaInflammasomesInterleukin-6LipopolysaccharidesMiceMice, Inbred MRL lprNLR Family, Pyrin Domain-Containing 3 ProteinProto-Oncogene Proteins c-pim-1Adenosine TriphosphateCCAAT-Enhancer-Binding Protein-betaCebpb protein, mouseInflammasomesInterleukin-6LipopolysaccharidesNLR Family, Pyrin Domain-Containing 3 ProteinPim1 protein, mouseProto-Oncogene Proteins c-pim-1

Identifiers

PMID36248187
PMCPMC9553452
OpenAlexW4296784189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.