Evidence map›Paper›PMID 36248098›Full record

ReviewBrain & spine2022

Surgical outcomes of pediatric brain tumors in Sub-Saharan Africa: A systematic review.

Vendela Herdell, Philipp Lassarén, Frederick A Boop, Jiri Bartek, Enoch O Uche, Magnus Tisell

Open access · goldAbstract readReview
In one paragraph

Review in Brain & spine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Global pediatric craniopharyngioma management modalities and outcomes.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Vendela HerdellKarolinska Institutet, Stockholm, Sweden.
Philipp LassarénKarolinska Institutet, Stockholm, Sweden.
Frederick A BoopDepartment of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, USA.
Jiri BartekDepartment of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden.
Enoch O UcheDivision of Neurosurgery, Department of Surgery, University of Nigeria Nsukka, Ituku-Ozalla Campus, Enugu, Nigeria.
Magnus TisellDepartment of Neurosurgery, Sahlgrenska University Hospital, Gothenburg, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SESahlgrenska University Hospital · SESt. Jude Children's Research Hospital · USUniversity of Nigeria Teaching Hospital · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pediatric Brain Tumors (PBT) are a common cause of cancer-related mortality globally. Contrary to high-income countries (HIC), survival rates in low-and-middle income countries (LMIC) remains low despite advances in neurosurgical care and diagnostics over the past decades. The aim of this systematic review was to investigate the surgical outcomes for PBT in Sub-Saharan Africa, and the distribution of PBT types. Methods: A systematic review was conducted on PubMed, for all available literature on the surgical outcomes of PBT in Sub-Saharan Africa, published before May 3, 2022. Two reviewers performed abstract, full text screening and data collection independently, resolving any conflicts by consensus. Results: The search yielded 256 studies, of which 22 met the inclusion criteria, amounting to a total of 243 patients. Nigeria was the country with most data. Only subgroups of patients could be extracted from 12 studies, and variables of interest in 6 studies had inconsistent sample sizes. The age centered around 9 years, and there were approximately equal number of girls and boys. The most common tumor was medulloblastoma, followed by craniopharyngioma and astrocytoma. There was large heterogeneity in the reporting of outcomes, and a trend was difficult to discern, considering the large number of different tumor types and different extents of resection. Discussion and conclusion: Data is insufficient and inconsistent, precluding statistical conclusions. There is a need for more studies in the field.

Indexed as

Brain tumorNeurosurgeryOutcomesPediatricSub-Saharan Africa

Identifiers

PMID36248098
PMCPMC9560713
OpenAlexW4283797524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.