Evidence map›Paper›PMID 36247882›Full record

ArticlePulmonary medicine2022

A Metabolic Activity Recovery of the Intestinal Microbiota in the Patients with Bronchial Asthma.

Mariusz Ozimek, Vladimir Ivashkin, Oksana Zolnikova, Nino Potskherashvili, Konstantin Ivashkin, Natiya Dzhakhaya, Anastasia Kurbatova, Kira Kryuchkova, Victoria Zaborova

Abstract read
In one paragraph

Article in Pulmonary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mariusz OzimekInstitute of Sport, Department of Track and Field's Sports, University of Physical Education, 31-571 Krakow, Poland.ORCID https://orcid.org/0000-0002-9282-5725
Vladimir IvashkinInstitute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID https://orcid.org/0000-0002-6815-6015
Oksana ZolnikovaInstitute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID https://orcid.org/0000-0002-6701-789X
Nino PotskherashviliVasilenko Clinic of Internal Disease Propedeutics, Gastroenterology, And Hepatology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID https://orcid.org/0000-0003-1973-3602
Konstantin IvashkinInstitute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID https://orcid.org/0000-0002-5699-541X
Natiya DzhakhayaInstitute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID https://orcid.org/0000-0001-5081-3390
Anastasia KurbatovaInstitute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID https://orcid.org/0000-0003-1241-7551
Kira KryuchkovaInstitute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID https://orcid.org/0000-0002-1172-9695
Victoria ZaborovaInstitute of Clinical Medicine, I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.ORCID https://orcid.org/0000-0001-5044-1152

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: It was established that the high biological diversity of intestinal microorganisms promotes the needed SCFAs production, which induces immune regulatory pathways and contributes to the anti-inflammatory response. Results: A normalization of the SCFA spectrum and anaerobic index for all of the studied patients were noted. Upon taking the probiotics, it was revealed in the patients without SIBO that the total content of fatty acids ( Conclusion: The obtained results demonstrate a potential opportunity of the drug influence on the active bacterial metabolites composition and amount in the intestinal biotope; as it was confirmed by the restoration of the intestinal microbiocenosis and microorganism habitat.

Indexed as

AsthmaGastrointestinal MicrobiomeAnti-Inflammatory AgentsButyratesFatty AcidsHumansAnti-Inflammatory AgentsButyratesFatty Acids

Identifiers

PMID36247882
PMCPMC9553837

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.