Evidence map›Paper›PMID 36247837›Full record

ArticleBrain, behavior, & immunity - health2022

Vagal control moderates the association between endothelial function and PTSD symptoms in women with T2DM.

Antonia V Seligowski, Ida T Fonkoue, Natalie C Noble, Drew Dixon, Rachel Gluck, Ye Ji Kim, Abigail Powers, Thaddeus W W Pace, Tanja Jovanovic, Guillermo Umpierrez and 4 more

Open access · goldAbstract read
In one paragraph

Article in Brain, behavior, & immunity - health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Higher arterial stiffness and blunted vagal control of the heart in young women with compared to without a clinical diagnosis of PTSD.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Antonia V SeligowskiDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
Ida T FonkoueDepartment of Rehabilitation Medicine, University of Minnesota Medical School, Minneapolis, MN, USA.
Natalie C NobleMcLean Hospital, Belmont, MA, USA.
Drew DixonDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Rachel GluckDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Ye Ji KimDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Abigail PowersDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Thaddeus W W PaceCollege of Nursing and College of Medicine (Psychiatry), University of Arizona, Tucson, AZ, USA.
Tanja JovanovicDepartment of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI, USA.
Guillermo UmpierrezDivision of Endocrinology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Kerry J ResslerDepartment of Psychiatry, Harvard Medical School, Boston, MA, USA.
Arshed A QuyyumiDivision of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Vasiliki MichopoulosDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Charles F GillespieDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Emory University · USMcLean Hospital · USEmory National Primate Research CenterHarvard University · USUniversity of Arizona · USUniversity of Minnesota Medical Center · USWayne State University · US

Funding

Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Sex Differences in Major Depression, Part II: Impact of Prenatal Immune, Autonomic and Neurovascular FunctionU54MH118919 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI STUART A. TOBET · 2020 to 2026
$12.7M
NIH HHS P51 OD011132NIMH NIH HHS U54 MH118919
6 · The paper itself

Abstract

Background: Individuals with posttraumatic stress disorder (PTSD) are more likely to present with metabolic diseases such as type-2 diabetes mellitus (T2DM), and cardiovascular dysfunction has been implicated in this link. These diseases disproportionately affect women and individuals exposed to chronic environmental stressors (e.g., community violence, poverty). We examined associations among PTSD, cardiovascular indices, and metabolic function in highly trauma-exposed Black women with T2DM. Methods: Participants ( Results: Of the cardiovascular indices, only FMD was significantly associated with PTSD symptoms (CAPS Avoidance symptoms; Conclusions: Our results indicate that endothelial function is significantly related to PTSD and glucose tolerance, over and above other cardiovascular measures (HR, BP, RSA). Further, our results suggest that low RSA may be a risk factor for the link between poor endothelial function and PTSD in women with T2DM.

Indexed as

CardiovascularMetabolicPTSDTraumaType-II diabetes Mellitus

Identifiers

PMID36247837
PMCPMC9557816
OpenAlexW4300861089

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.