Evidence map›Paper›PMID 36247670›Full record

ArticleFrontiers in chemistry2022

Cytotoxic mixed-ligand complexes of Cu(II): A combined experimental and computational study.

Mamaru Bitew Alem, Tadewos Damena, Tegene Desalegn, Moses Koobotse, Rajalakshmanan Eswaramoorthy, Kennedy J Ngwira, Japheth O Ombito, Matshediso Zachariah, Taye B Demissie

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In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Mamaru Bitew AlemDepartment of Applied Chemistry, Adama Science and Technology University, Adama, Ethiopia.
Tadewos DamenaDepartment of Applied Chemistry, Adama Science and Technology University, Adama, Ethiopia.
Tegene DesalegnDepartment of Applied Chemistry, Adama Science and Technology University, Adama, Ethiopia.
Moses KoobotseSchool of Allied Health Professions, University of Botswana, Gaborone, Botswana.
Rajalakshmanan EswaramoorthyDepartment of Biomaterials, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Kennedy J NgwiraMolecular Sciences Institute, School of Chemistry, University of the Witwatersrand, Johannesburg, South Africa.
Japheth O OmbitoDepartment of Chemistry, University of Botswana, Gaborone, Botswana.
Matshediso ZachariahSchool of Allied Health Professions, University of Botswana, Gaborone, Botswana.
Taye B DemissieDepartment of Chemistry, University of Botswana, Gaborone, Botswana.
University of Botswana · BWAdama Science and Technology University · ETSaveetha University · INUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report the synthesis of mixed-ligand Cu(II) complexes of metformin and ciprofloxacin drugs together with 1,10-phenanthroline as a co-ligand. The synthesized complexes were characterized using different spectroscopic and spectrometric techniques.

Indexed as

antibacterial activityBOILED-eggCu(II) complexescytotoxicityDFTMCF-7molecular docking

Identifiers

PMID36247670
PMCPMC9557196
OpenAlexW4302287974

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.