ArticleFrontiers in plant science2022
Too Dense or Not Too Dense: Higher Planting Density Reduces Cannabinoid Uniformity but Increases Yield/Area in Drug-Type Medical Cannabis.
Article in Frontiers in plant science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 49 citations in OpenAlex.
- Integrating Genetic and Biotechnological Approaches to Enhance High-CBD Cannabis sativa L. Cultivation for Medicinal Purposes.Molecular biotechnology · 2026Review
- High-THC Cannabis sativa in a New York greenhouse: yield and economic factors.Journal of cannabis research · 2026Article
- Exploring Linalool-Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition.Phytotherapy research : PTR · 2026Review
- Article
- The power of zinc: excess and deficiency of Zn decrease cannabinoids in cannabis without Zn toxicity concerns to consumers.Journal of cannabis research · 2026Article
- Classifying Cannabis sativa chemovars using K-means analysis of elemental composition.Journal of cannabis research · 2025Article
- Genotype and chemotype insights of high-THC medicinal Cannabis sativa L.: the role of SSR markers in the identification of cultivars.Journal of cannabis research · 2025Article
- Influence of Agronomic Practices on the Bioactive Compound Production inInternational journal of molecular sciences · 2025Article
- Improved Biomass Production and Secondary Metabolism: A Critical Review of Grafting inPlants (Basel, Switzerland) · 2025Review
- Bracts, Buds, and Biases: Uncovering Gaps in Trichome Density Quantification and Cannabinoid Concentration inPlants (Basel, Switzerland) · 2025Review
- Variability of total THC in greenhouse cultivated dried Cannabis.Scientific reports · 2025Article
- Unravelling herbicide stress and its impact on metabolite profiling in Cannabis sativa: an investigative study.Journal of cannabis research · 2025Article
- Subcanopy and Inter-Canopy Supplemental Light Enhances and Standardizes Yields in Medicinal Cannabis (Plants (Basel, Switzerland) · 2025Article
- Is nitrogen-modified atmosphere packaging a tool for retention of volatile terpenes and cannabinoids in stored Cannabis sativa inflorescence?Journal of cannabis research · 2024Article
- Selected cannabis cultivars modulate glial activation: in vitro and in vivo studies.Journal of cannabis research · 2024Article
- Article
- Effect of saline irrigation and plant-based biostimulant application on fiber hemp (Frontiers in plant science · 2024Article
- Investigating how nitrogen nutrition and pruning impacts on CBD and THC concentration and plant biomass of Cannabis sativa.Scientific reports · 2023Article
- Correlations among morphological and biochemical traits in high-cannabidiol hemp (Plant direct · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A major challenge for utilizing cannabis for modern medicine is the spatial variability of cannabinoids in the plant, which entail differences in medical potency. Since secondary metabolism is affected by environmental conditions, a key trigger for the variability in secondary metabolites throughout the plant is variation in local micro-climates. We have, therefore, hypothesized that plant density, which is well-known to alter micro-climate in the canopy, affects spatial standardization, and concentrations of cannabinoids in cannabis plants. Canopy density is affected by shoot architecture and by plant spacing, and we have therefore evaluated the interplay between plant architecture and plant density on the standardization of the cannabinoid profile in the plant. Four plant architecture modulation treatments were employed on a drug-type medicinal cannabis cultivar, under a density of 1 or 2 plants/m
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.