ArticleFrontiers in cardiovascular medicine2022
Catheter ablation in patients with ventricular fibrillation by purkinje de-networking.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 18 citations in OpenAlex.
- Purkinje de-networking for refractory short-coupled premature ventricular contraction-triggered ventricular fibrillation in dextrocardia with situs inversus.HeartRhythm case reports · 2026Article
- Idiopathic Ventricular Fibrillation Triggered by Purkinje-Related Extrasystoles: State-of-the-Art and Novel Therapeutic Approaches.Journal of cardiovascular electrophysiology · 2026Review
- Utilizing stored implanted cardiac defibrillator electrograms to target localized fascicular denetworking in catheter ablation of ventricular fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Mapping and ablation of ventricular fibrillation substrate.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Review
- Percutaneous renal sympathetic denervation combined with empirical Purkinje de-networking for electrical storm in congenital long QT syndrome after cardiac sympathetic denervation: a case report with two consecutive patients.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026Article
- Radiofrequency Ablation and Right Purkinje De-Networking for Moderator Band PVC-Induced VF: Broadening the Therapeutic Landscape.JACC. Case reports · 2026Article
- Purkinje trigger mapping in postinfarction ventricular fibrillation storm with ventricular abnormal activities detection.HeartRhythm case reports · 2026Article
- Fascicular/Purkinje Tissue Colocalized With Scar in Cardiomyopathy Patients Undergoing Ventricular Fibrillation Ablation.Pacing and clinical electrophysiology : PACE · 2025Observational
- Editorial: Advancing our understanding of the cardiac conduction system to prevent arrhythmias.Frontiers in physiology · 2025Article
- Contemporary Trends in Pulsed Field Ablation for Cardiac Arrhythmias.Journal of cardiovascular development and disease · 2024Review
- Distribution characteristics of Purkinje fibres in the canine left ventricle.Journal of cellular and molecular medicine · 2024Article
- Significance of extensive ablation targeting Purkinje-muscle junction of all the left fascicles for suppressing Purkinje-related ventricular arrhythmias: A case report.HeartRhythm case reports · 2024Article
- Purkinje de-networking using a ripple map with a novel multielectrode mapping catheter for a ventricular fibrillation storm in a patient supported by an Impella device after an acute coronary syndrome.HeartRhythm case reports · 2024Article
- Successful ablation of Purkinje ectopy-triggered ventricular fibrillation storm in a patient with orthotopic heart transplantation and severe SARS-CoV-2 pneumonia: a case report.European heart journal. Case reports · 2024Article
- Successful ablation of ventricular fibrillation storm triggered by premature ventricular constructions after reperfusion of septal scar: let sleeping dogs lie.European heart journal. Case reports · 2024Article
- Catheter Ablation for Tachyarrhythmias in Left Ventricular Assist Device Recipients: Clinical Significance and Technical Tips.Journal of clinical medicine · 2023Review
- Successful catheter ablation of ventricular fibrillation storm in acute myocardial infarction by eliminating triggering premature ventricular contraction at the remote site from the exit.HeartRhythm case reports · 2023Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Ventricular fibrillation (VF) is a leading cause of cardiovascular death worldwide. However, recurrence rates of arrhythmia are high leading to mortality and morbidity. Recently, Purkinje fibers have been identified as potential sources of VF initiation and maintenance. Aim: The study analyzes the feasibility and effectiveness of catheter ablation in patients with recurrent VF by specific Purkinje de-networking (PDN). Methods: Consecutive patients with recurrent VF undergoing PDN were included in this observational study. The procedural endpoint was the non-inducibility of sustained ventricular arrhythmia. A three-dimensional -anatomical mapping was conducted, and the specific cardiac conduction system and Purkinje fibers were tagged. All detectable Purkinje signals were ablated in the left ventricle (LV). Additional right ventricular (RV) PDN was performed in case of VF inducibility after LV ablation. Follow-up was performed by patient visits at our outpatient clinic including device interrogation and by telephone interviews. Results: Eight patients were included in the study. Six patients were females (75%); the median age during the procedure was 43 [37;57] years and the median body mass index was 24 [23;33] kg/m Conclusion: Purkinje de-networking represents a novel treatment option for patients with recurrent VF without arrhythmia substrate or specific arrhythmia triggers with promising results in terms of efficiency and feasibility. Larger and more prospective studies are needed for a systematic evaluation.
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