Evidence map›Paper›PMID 36247313›Full record

ArticleDEN open2023

Carcinoembryonic antigen levels in pancreatic juice are associated with histological subtypes of intraductal papillary mucinous neoplasm of the pancreas.

Hiroshi Hayakawa, Mitsuharu Fukasawa, Shinichi Takano, Hiroko Shindo, Ei Takahashi, Satoshi Kawakami, Yoshimitsu Fukasawa, Natsuhiko Kuratomi, Tadashi Sato, Makoto Kadokura and 9 more

Open access · goldAbstract read
In one paragraph

Article in DEN open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Hiroshi HayakawaFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.ORCID https://orcid.org/0000-0001-5434-048X
Mitsuharu FukasawaFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.ORCID https://orcid.org/0000-0003-3137-9685
Shinichi TakanoFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Hiroko ShindoFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Ei TakahashiFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Satoshi KawakamiFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Yoshimitsu FukasawaFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Natsuhiko KuratomiFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Tadashi SatoFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Makoto KadokuraFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Sumio HiroseFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Shinya MaekawaFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Taisuke InoueFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Tatsuya YamaguchiFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Shota HaraiFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Hiromichi KawaidaFirst Department of Surgery Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Hiroshi KonoFirst Department of Surgery Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Kunio MochizukiDepartment of Pathology Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
Nobuyuki EnomotoFirst Department of Internal Medicine Faculty of Medicine, Graduate School of Medicine University of Yamanashi Yamanashi Japan.
University of Yamanashi · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The present study aimed to examine the correlation between preoperative carcinoembryonic antigen levels in pancreatic juice (PJ-CEA) and the histological subtype of intraductal papillary mucinous neoplasm (IPMN). Methods: We enrolled IPMN patients who underwent endoscopic retrograde pancreatography between March 2002 and March 2018. Clinical factors associated with IPMN histological subtypes of 67 patients who underwent surgery were analyzed. Furthermore, the relationship between CEA immunohistochemistry findings and histological subtypes was investigated. Results: Median PJ-CEA were 15 ng/ml in the gastric type, 150 ng/ml in the intestinal type, and 175 ng/ml in the pancreatobiliary type. Both intestinal and pancreatobiliary types had significantly higher PJ-CEA than the gastric type ( Conclusion: PJ-CEA was an independent predictor of IPMN histological subtypes in a preoperative setting. High PJ-CEA predict the non-gastric type, while low PJ-CEA predict the gastric type.

Indexed as

carcinoembryonic antigenendoscopic retrograde pancreatographyhistological subtypeintraductal papillary mucinous neoplasmpancreatic juice

Identifiers

PMID36247313
PMCPMC9552336
OpenAlexW4304187593

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.