Evidence map›Paper›PMID 36247269›Full record

ArticleAmerican journal of translational research2022

CT-guided percutaneous chemical ablation combined with radiofrequency ablation for hepatocellular carcinomas in high-risk locations: lobaplatin vs. ethanol.

Wen-Dong Li, Xiao-Yan Ding, Wei Sun, Xiao-Di Guo, Sha-Sha Sun, Yan-Jun Shen, Li Li, Wei Li, Jing-Long Chen

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Wen-Dong LiDepartment of Cancer Center, Beijing Ditan Hospital, Capital Medical University Beijing, China.
Xiao-Yan DingDepartment of Cancer Center, Beijing Ditan Hospital, Capital Medical University Beijing, China.
Wei SunDepartment of Cancer Center, Beijing Ditan Hospital, Capital Medical University Beijing, China.
Xiao-Di GuoDepartment of Cancer Center, Beijing Ditan Hospital, Capital Medical University Beijing, China.
Sha-Sha SunDepartment of Cancer Center, Beijing Ditan Hospital, Capital Medical University Beijing, China.
Yan-Jun ShenDepartment of Cancer Center, Beijing Ditan Hospital, Capital Medical University Beijing, China.
Li LiDepartment of Cancer Center, Beijing Ditan Hospital, Capital Medical University Beijing, China.
Wei LiDepartment of Cancer Center, Beijing Ditan Hospital, Capital Medical University Beijing, China.
Jing-Long ChenDepartment of Cancer Center, Beijing Ditan Hospital, Capital Medical University Beijing, China.
Beijing Ditan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To retrospectively compare the clinical efficacy and safety of CT-guided percutaneous injection of lobaplatin vs. ethanol for chemical ablation combined with radiofrequency ablation (RFA) in patients with hepatocellular carcinomas (HCCs) in high-risk locations. From January 2017 to June 2018, a total of 41 patients with HCCs in high-risk locations were enrolled and divided into two groups: percutaneous lobaplatin injection (PLI+RFA) group and percutaneous ethanol injection (PEI+RFA) group. The mixture of lobaplatin or ethanol was accurately injected into the high-risk part of the tumors, while RFA ablated the non-high-risk part. The efficacy and safety were compared between the two groups. 41 patients had 51 lesions in high-risk locations, including 24 cases with 30 lesions in PLI+RFA group and 17 cases with 21 lesions in PEI+RFA group. The complete ablation rate was 93.3% (28/30) in PLI+RFA group and 90.5% (19/21) in PEI+RFA group (P=1.000). The 2-year local tumor progression rate of PLI+RFA group and PEI+RFA group was 20.0% (6/30) and 19.0% (4/21), respectively (P=1.000). No significant differences were found in time to progression and overall survival between the two groups (P=0.501 and P=0.424, respectively). The incidence and severity of adverse events between the two groups were similar (P > 0.05). No severe complications were observed in both groups. Percutaneous lobaplatin injection combined with RFA in the treatment of HCC in high-risk locations may achieve the complete ablation rate similar to percutaneous ethanol injection combined with RFA, but further research is needed to confirm.

Indexed as

chemical ablationHepatocellular carcinomahigh-risk locationradiofrequency ablation

Identifiers

PMID36247269
PMCPMC9556503
OpenAlexW4306669355

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.