Evidence map›Paper›PMID 36247177›Full record

ArticleHeliyon2022

Effect of CD44 signal axis in the gain of mesenchymal stem cell surface antigens from synovial fibroblasts

Masaaki Isono, Jun Takeuchi, Ami Maehara, Yusuke Nakagawa, Hiroki Katagiri, Kazumasa Miyatake, Ichiro Sekiya, Hideyuki Koga, Yoshinori Asou, Kunikazu Tsuji

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Masaaki IsonoDepartment of Joint Surgery and Sports Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Jun TakeuchiMedical Affairs Unit, Seikagaku Corporation, Tokyo, Japan.
Ami MaeharaDepartment of Cartilage Regeneration, Tokyo Medical and Dental University, Tokyo, Japan.
Yusuke NakagawaDepartment of Joint Surgery and Sports Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Hiroki KatagiriDepartment of Joint Surgery and Sports Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Kazumasa MiyatakeDepartment of Joint Surgery and Sports Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Ichiro SekiyaCenter for Stem Cell and Regenerative Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Hideyuki KogaDepartment of Joint Surgery and Sports Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Yoshinori AsouDepartment of Nano-Bioscience, Tokyo Medical and Dental University, Tokyo, Japan.
Kunikazu TsujiDepartment of Cartilage Regeneration, Tokyo Medical and Dental University, Tokyo, Japan.
Tokyo Medical and Dental University · JPSeikagaku Corporation (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue-residing mesenchymal stromal/stem cells (MSCs) have multipotent characteristics that are important for adult tissue homeostasis and tissue regeneration after injury. We previously reported that fibroblastic cells isolated from the synovial membrane in the knee joint give rise to cells with MSC characteristics in a two-dimensional culture. To explore the molecular mechanisms underlying these hyperplastic properties, we performed time-course surface antigen expression analyses during

Indexed as

Hyaluronic acidMesenchymal stromal/stem cell (MSC)PlasticitySurface antigenSynovial fibroblast

Identifiers

PMID36247177
PMCPMC9557910
OpenAlexW4297328651

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.