Evidence map›Paper›PMID 36247006›Full record

ArticleFrontiers in cell and developmental biology2022

An expanded population of CD8

Genevieve T Clutton, Ann Marie K Weideman, Nilu P Goonetilleke, Toby Maurer

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Increased CD8Immunology · 2025
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Genevieve T CluttonDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Ann Marie K WeidemanDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Nilu P GoonetillekeDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Toby MaurerDepartment of Dermatology, Indiana University, Indianapolis, IN, United States.
University of North Carolina at Chapel Hill · USIndiana University – Purdue University Indianapolis · US

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Biostatistics for Research in Genomics and CancerT32CA106209 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JOSEPH G IBRAHIM, Naim Ur Rashid · 2004 to 2026
$4.8M
NCI NIH HHS T32 CA106209NIAID NIH HHS P30 AI050410
6 · The paper itself

Abstract

HIV-associated Kaposi's sarcoma (KS), which is caused by Kaposi's sarcoma-associated herpesvirus, usually arises in the context of uncontrolled HIV replication and immunosuppression. However, disease occasionally occurs in individuals with durable HIV viral suppression and CD4 T cell recovery under antiretroviral therapy (ART). The underlying mechanisms associated with this phenomenon are unclear. Suppression of viral infections can be mediated by CD8 T cells, which detect infected cells

Indexed as

CD8 coreceptorHIVKaposi’s sarcomaKSHVmetabolismmitochondriasenescenceT cells

Identifiers

PMID36247006
PMCPMC9557199
OpenAlexW4298001048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.