ArticleFrontiers in endocrinology2022
Association of obesity phenotypes with left ventricular mass index and left ventricular hypertrophy in children and adolescents.
Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Cardiometabolic risk in children and adolescents with obesity: a position paper of the Italian Society for Pediatric Endocrinology and Diabetology.Italian journal of pediatrics · 2024Guideline
- Childhood Obesity: A Multisystem Challenge Linking Hypertension, NAFLD, and Sleep Apnea.Medical sciences (Basel, Switzerland) · 2026Review
- Factors associated with left ventricular mass during disease modifying antirheumatic drug therapy in patients with rheumatoid arthritis: the Joint Heart study.International journal of cardiology. Cardiovascular risk and prevention · 2025Article
- Targeting Myocardial Mechanics in Children and Adolescents with Obesity and Non-Elevated Blood Pressure: A Meta-Regression Study.Diseases (Basel, Switzerland) · 2025Review
- The correlation between insulin-like growth factor 1 and left ventricular mass index in obese children.BMC endocrine disorders · 2025Article
- Beyond Cardiometabolic: Health Disorders Risk in Metabolically Healthy Obese Children - A Systematic Review and Meta-Analysis of 19,119 Children.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Review
- Non-Pharmacological Treatment for Cardiovascular Risk Prevention in Children and Adolescents with Obesity.Nutrients · 2024Review
- Association Between Elevated Body Mass Index and Cardiac Organ Damage in Children and Adolescents: Evidence and Mechanisms.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024Article
- Article
- Trajectories in waist circumference and waist-to-height ratio with left ventricular hypertrophy in childhood.Frontiers in nutrition · 2024Article
- Obesity phenotypes and cardiovascular risk: From pathophysiology to clinical management.Reviews in endocrine & metabolic disorders · 2023Review
- Skeptical Look at the Clinical Implication of Metabolic Syndrome in Childhood Obesity.Children (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been argued that metabolically healthy obesity (MHO) does not increase the risk of cardiovascular disease. The aim of this study is to evaluate whether, in a population of obese children/adolescents, the metabolically unhealthy obesity (MUO) phenotype is associated with higher left ventricular mass index and/or higher prevalence of left ventricular hypertrophy than the MHO phenotype. We also tested whether the addition of an insulin resistance index (HOMA-index >90th percentile by sex and age) and the presence of hyperuricemia (serum uric acid >90th percentile by sex and age) to the definition of MUO better identified obese children with early cardiac damage. Left ventricular hypertrophy was defined as the presence of left ventricular mass index greater than or equal to the age- and sex-specific 95th percentile. The study population included 459 obese children (males 53.2%, mean age 10.6 [standard deviation, 2.6] years), of whom 268 (58.4%) were MUO. The left ventricular mass index was higher in MUO children than in MHO children (37.8 vs 36.3 g/m
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