Evidence map›Paper›PMID 36246891›Full record

ReviewFrontiers in endocrinology2022

Membrane estrogen signaling in female reproduction and motivation.

Caroline S Johnson, Paul E Micevych, Paul G Mermelstein

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Caroline S JohnsonDepartment of Neuroscience, University of Minnesota, Minneapolis, MN, United States.
Paul E MicevychLaboratory of Neuroendocrinology, Department of Neurobiology, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA, United States.
Paul G MermelsteinDepartment of Neuroscience, University of Minnesota, Minneapolis, MN, United States.
University of Minnesota · USUniversity of California, Los Angeles · US

Funding

NEUROSCIENCE TRAINING IN DRUG ABUSE RESEARCHT32DA007234 · NIDA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Paul G Mermelstein, Jocelyn M Richard · 1986 to 2026
$10.9M
SEX STEROID ACTIVATION OF OPIOID CIRCUITS IN THE CNSR01DA013185 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MICEVYCH, PAUL E · 2001 to 2016
$5.0M
Physiology of Hypothalamic Neurosteroidal ProgesteroneR01HD042635 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MICEVYCH, PAUL E · 2003 to 2019
$4.8M
Modulation of sex steroid-induced female social behaviors in an animal modelR01HD098284 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MICEVYCH, PAUL E · 2020 to 2024
$2.1M
Estrogen Facilitation of Female Drug RelapseR01DA041808 · NIDA · UNIVERSITY OF MINNESOTA · PI MERMELSTEIN, PAUL G, THOMAS, MARK JOHN · 2016 to 2020
$2.0M
NICHD NIH HHS R01 HD042635NICHD NIH HHS R01 HD098284NIDA NIH HHS R01 DA013185NIDA NIH HHS R01 DA041808NIDA NIH HHS T32 DA007234
6 · The paper itself

Abstract

Estrogen receptors were initially identified in the uterus, and later throughout the brain and body as intracellular, ligand-regulated transcription factors that affect genomic change upon ligand binding. However, rapid estrogen receptor signaling initiated outside of the nucleus was also known to occur

Indexed as

Receptors, EstrogenReceptors, Metabotropic GlutamateEstrogensFemaleGlutamatesHumansLigandsMotivationReproductionEstrogensGlutamatesLigandsReceptors, EstrogenReceptors, Metabotropic Glutamateestrogenestrogen receptorsestrogen receptor signalingmembrane estrogen receptorsmetabotropic glutamate (mGlu) receptors

Identifiers

PMID36246891
PMCPMC9557733
OpenAlexW4297999885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.