ArticleBioactive materials2023
Design of single-phased magnesium alloys with typically high solubility rare earth elements for biomedical applications: Concept and proof.
Article in Bioactive materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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7 citing papers in PubMed, 30 citations in OpenAlex.
- The Effect of Three Kinds of Surface Treatment Methods on the Corrosion and Wear Resistance of AM60B Magnesium Alloy with La, Ce Addition.Materials (Basel, Switzerland) · 2026Article
- Biodegradable Magnesium-Based Implants in Sports Orthopedic Surgery: Advances in Alloy Design, Surface Engineering, and Translational Evidence.Bioengineering (Basel, Switzerland) · 2026Review
- Low addition of Er and Zn into biomedical magnesium with enhanced integrated properties for orthopedic applications:Bioactive materials · 2026Article
- [Applications and prospects of biodegradable rare earth magnesium alloys as bone implant materials].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025Review
- A hierarchical MgFBioactive materials · 2025Article
- [Latest research progress of rare earth-magnesium alloys in orthopedics].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Review
- Unraveling the Complex Interactions: Machine Learning Approaches to Predict Bacterial Survival against ZnO and Lanthanum-Doped ZnO Nanoparticles.Antibiotics (Basel, Switzerland) · 2024Article
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Authors and funding
21 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rare earth elements (REEs) have been long applied in magnesium alloys, among which the mischmetal-containing WE43 alloy has already got the CE mark approval for clinical application. A considerable amount of REEs (7 wt%) is needed in that multi-phased alloy to achieve a good combination of mechanical strength and corrosion resistance. However, the high complex RE addition accompanied with multiple second phases may bring the concern of biological hazards. Single-phased Mg-RE alloys with simpler compositions were proposed to improve the overall performance, i.e., "Simpler alloy, better performance". The single-phased microstructure can be successfully obtained with typical high-solubility REEs (Ho, Er or Lu) through traditional smelting, casting and extrusion in a wide compositional range. A good corrosion resistance with a macroscopically uniform corrosion mode was guaranteed by the homogeneously single-phased microstructure. The bimodal-grained structure with plenty of sub-grain microstructures allow us to minimize the RE addition to <1 wt%, without losing mechanical properties. The single-phased Mg-RE alloys show comparable mechanical properties to the clinically-proven Mg-based implants. They exhibited similar
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