Evidence map›Paper›PMID 36246642›Full record

ArticleFrontiers in genetics2022

Identification and characterization of extrachromosomal circular DNA in alcohol induced osteonecrosis of femoral head.

Tingting Zhou, Shiqiang Ma, Yunchao Zhao, Donghui Guo, Hengjun Wang, Mingjie Kuang, Xiaoming Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Tingting ZhouDepartment of Orthopedics, Traditional Chinese Medicine-Western Medicine Hospital of Cangzhou City, Cangzhou, China.
Shiqiang MaDepartment of Orthopedics, Traditional Chinese Medicine-Western Medicine Hospital of Cangzhou City, Cangzhou, China.
Yunchao ZhaoDepartment of Orthopedics, Traditional Chinese Medicine-Western Medicine Hospital of Cangzhou City, Cangzhou, China.
Donghui GuoDepartment of Orthopedics, Traditional Chinese Medicine-Western Medicine Hospital of Cangzhou City, Cangzhou, China.
Hengjun WangDepartment of Orthopedics, Traditional Chinese Medicine-Western Medicine Hospital of Cangzhou City, Cangzhou, China.
Mingjie KuangHebei Key Laboratory of Integrated Traditional and Western Medicine in Osteoarthrosis Research (Preparing), Cangzhou, China.
Xiaoming LiDepartment of Orthopedics, Traditional Chinese Medicine-Western Medicine Hospital of Cangzhou City, Cangzhou, China.
People's Hospital of Cangzhou · CNShandong Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcohol-induced osteonecrosis of the femoral head (AIONFH) is a complicated refractory bone disease seen in the clinic. The pathogenesis of AIONFH is still controversial. Extrachromosomal circular DNA (eccDNA) elements have been indicated ubiquitously exist in eukaryotic genomes. However, the characteristics and biological functions of eccDNAs remain unclear in AIONFH. In this study, eccDNAs from AIONFH samples (

Indexed as

alcohol induced osteonecrosis of femoral headbioinformaticschromosomal instabilityextrachromosomal circular DNAfunction of eccDNA

Identifiers

PMID36246642
PMCPMC9561878
OpenAlexW4298143692

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.