Evidence map›Paper›PMID 36246573›Full record

ArticleiScience2022

Linking contact tracing with genomic surveillance to deconvolute SARS-CoV-2 transmission on a university campus.

Jacquelyn Turcinovic, Kayla Kuhfeldt, Madison Sullivan, Lena Landaverde, Judy T Platt, Lynn Doucette-Stamm, William P Hanage, Davidson H Hamer, Catherine Klapperich, Hannah E Landsberg and 1 more

Abstract read
In one paragraph

Article in iScience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jacquelyn TurcinovicDepartment of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA.
Kayla KuhfeldtStudent Health Services, Boston University, Boston, MA 02215, USA.
Madison SullivanStudent Health Services, Boston University, Boston, MA 02215, USA.
Lena LandaverdeDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
Judy T PlattStudent Health Services, Boston University, Boston, MA 02215, USA.
Lynn Doucette-StammBU Clinical Testing Laboratory, Research Department, Boston University, Boston, MA 02215, USA.
William P HanageCenter for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Davidson H HamerNational Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02118, USA.
Catherine KlapperichDepartment of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
Hannah E LandsbergStudent Health Services, Boston University, Boston, MA 02215, USA.
John H ConnorDepartment of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contact tracing and genomic data, approaches often used separately, have both been important tools in understanding the nature of SARS-CoV-2 transmission. Linked analysis of contact tracing and sequence relatedness of SARS-CoV-2 genomes from a regularly sampled university environment were used to build a multilevel transmission tracing and confirmation system to monitor and understand transmission on campus. Our investigation of an 18-person cluster stemming from an athletic team highlighted the importance of linking contact tracing and genomic analysis. Through these findings, it is suggestive that certain safety protocols in the athletic practice setting reduced transmission. The linking of traditional contact tracing with rapid-return genomic information is an effective approach for differentiating between multiple plausible transmission scenarios and informing subsequent public health protocols to limit disease spread in a university environment.

Indexed as

Clinical findingGenomicsHealth sciences

Identifiers

PMID36246573
PMCPMC9554197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.