Evidence map›Paper›PMID 36246284›Full record

ReviewFrontiers in microbiology2022

Physiologically relevant microsystems to study viral infection in the human liver.

Dennis McDuffie, David Barr, Ashutosh Agarwal, Emmanuel Thomas

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dennis McDuffieDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL, United States.
David BarrDepartment of Pathology and Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL, United States.
Ashutosh AgarwalDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL, United States.
Emmanuel ThomasDepartment of Biomedical Engineering, University of Miami, Coral Gables, FL, United States.
University of Miami · USSylvester Comprehensive Cancer Center · US

Funding

Revealing HIV-1 persistence in myeloid cell reservoirsR01MH116701 · NIMH · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Mario Stevenson · 2018 to 2026
$4.0M
A MULTIFACETED APPROACH TO STUDY TISSUE AND CELL TYPE SPECIFIC MOLECULAR MECHANISMS OF THE HOST RESPONSE TO ACUTE/CHRONIC VIRAL INFECTIONR35GM124915 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Emmanuel Thomas · 2017 to 2026
$3.9M
Defining a Role for Liver Myeloid Cells in Viral Persistence under ART-SUPPLEMENT 1R01DK131533 · NIDDK · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Mario Stevenson, Emmanuel Thomas · 2022 to 2026
$2.5M
NIDDK NIH HHS R01 DK131533NIGMS NIH HHS R35 GM124915NIMH NIH HHS R01 MH116701
6 · The paper itself

Abstract

Viral hepatitis is a leading cause of liver disease and mortality. Infection can occur acutely or chronically, but the mechanisms that govern the clearance of virus or lack thereof are poorly understood and merit further investigation. Though cures for viral hepatitis have been developed, they are expensive, not readily accessible in vulnerable populations and some patients may remain at an increased risk of developing hepatocellular carcinoma (HCC) even after viral clearance. To sustain infection

Indexed as

hepatitis B virushepatitis C virushepatocellular carcinomain vitro disease modelliver-on-chip

Identifiers

PMID36246284
PMCPMC9555087
OpenAlexW4297475116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.